Host: |
Rabbit |
Applications: |
WB/IF |
Reactivity: |
Human/Mouse/Rat |
Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Short Description: |
Rabbit polyclonal antibody anti-PHGDH (264-533) is suitable for use in Western Blot and Immunofluorescence research applications. |
Clonality: |
Polyclonal |
Conjugation: |
Unconjugated |
Isotype: |
IgG |
Formulation: |
PBS with 0.02% Sodium Azide, 50% Glycerol, pH7.3. |
Purification: |
Affinity purification |
Dilution Range: |
WB 1:500-1:2000IF/ICC 1:50-1:200 |
Storage Instruction: |
Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Gene Symbol: |
PHGDH |
Gene ID: |
26227 |
Uniprot ID: |
SERA_HUMAN |
Immunogen Region: |
264-533 |
Immunogen: |
Recombinant fusion protein containing a sequence corresponding to amino acids 264-533 of human PHGDH (NP_006614.2). |
Immunogen Sequence: |
EEPPRDRALVDHENVISCPH LGASTKEAQSRCGEEIAVQF VDMVKGKSLTGVVNAQALTS AFSPHTKPWIGLAEALGTLM RAWAGSPKGTIQVITQGTSL KNAGNCLSPAVIVGLLKEAS KQADVNLVNAKLLVKEAGLN VTTSHSPAAPGEQGFGECLL AVALAGAPYQAVGLVQGTTP VLQGLNGAVFRPEVPLRRDL PLLLFRTQTSDPAMLPTMIG LLAEAGVRLLSYQTSLVSD |
Function | Catalyzes the reversible oxidation of 3-phospho-D-glycerate to 3-phosphonooxypyruvate, the first step of the phosphorylated L-serine biosynthesis pathway. Also catalyzes the reversible oxidation of 2-hydroxyglutarate to 2-oxoglutarate and the reversible oxidation of (S)-malate to oxaloacetate. |
Protein Name | D-3-Phosphoglycerate Dehydrogenase3-Pgdh2-Oxoglutarate ReductaseMalate Dehydrogenase |
Database Links | Reactome: R-HSA-977347 |
Alternative Antibody Names | Anti-D-3-Phosphoglycerate Dehydrogenase antibodyAnti-3-Pgdh antibodyAnti-2-Oxoglutarate Reductase antibodyAnti-Malate Dehydrogenase antibodyAnti-PHGDH antibodyAnti-PGDH3 antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance