• Immunofluorescence analysis of L929 cells using PHGDH antibody (STJ11100850) at dilution of 1:100. Blue: DAPI for nuclear staining.
  • Immunofluorescence analysis of H9C2 cells using PHGDH antibody (STJ11100850) at dilution of 1:100. Blue: DAPI for nuclear staining.
  • Immunofluorescence analysis of U2OS cells using PHGDH antibody (STJ11100850) at dilution of 1:100. Blue: DAPI for nuclear staining.

Anti-PHGDH antibody (264-533) (STJ11100850)

SKU:
STJ11100850

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Host: Rabbit
Applications: WB/IF
Reactivity: Human/Mouse/Rat
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description: Rabbit polyclonal antibody anti-PHGDH (264-533) is suitable for use in Western Blot and Immunofluorescence research applications.
Clonality: Polyclonal
Conjugation: Unconjugated
Isotype: IgG
Formulation: PBS with 0.02% Sodium Azide, 50% Glycerol, pH7.3.
Purification: Affinity purification
Dilution Range: WB 1:500-1:2000
IF/ICC 1:50-1:200
Storage Instruction: Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.
Gene Symbol: PHGDH
Gene ID: 26227
Uniprot ID: SERA_HUMAN
Immunogen Region: 264-533
Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 264-533 of human PHGDH (NP_006614.2).
Immunogen Sequence: EEPPRDRALVDHENVISCPH LGASTKEAQSRCGEEIAVQF VDMVKGKSLTGVVNAQALTS AFSPHTKPWIGLAEALGTLM RAWAGSPKGTIQVITQGTSL KNAGNCLSPAVIVGLLKEAS KQADVNLVNAKLLVKEAGLN VTTSHSPAAPGEQGFGECLL AVALAGAPYQAVGLVQGTTP VLQGLNGAVFRPEVPLRRDL PLLLFRTQTSDPAMLPTMIG LLAEAGVRLLSYQTSLVSD
Function Catalyzes the reversible oxidation of 3-phospho-D-glycerate to 3-phosphonooxypyruvate, the first step of the phosphorylated L-serine biosynthesis pathway. Also catalyzes the reversible oxidation of 2-hydroxyglutarate to 2-oxoglutarate and the reversible oxidation of (S)-malate to oxaloacetate.
Protein Name D-3-Phosphoglycerate Dehydrogenase
3-Pgdh
2-Oxoglutarate Reductase
Malate Dehydrogenase
Database Links Reactome: R-HSA-977347
Alternative Antibody Names Anti-D-3-Phosphoglycerate Dehydrogenase antibody
Anti-3-Pgdh antibody
Anti-2-Oxoglutarate Reductase antibody
Anti-Malate Dehydrogenase antibody
Anti-PHGDH antibody
Anti-PGDH3 antibody

Information sourced from Uniprot.org

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