• Western blot analysis of extracts of various cell lines, using PEX7 antibody (STJ29024) at 1:1000 dilution. Secondary antibody: HRP Goat Anti-rabbit IgG (H+L) at 1:10000 dilution. Lysates/proteins: 25ug per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit. Exposure time: 90s.

Anti-PEX7 antibody (1-240) (STJ29024)

SKU:
STJ29024

£169.50 - £449.50
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Host: Rabbit
Applications: WB
Reactivity: Human/Mouse/Rat
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description: Rabbit polyclonal antibody anti-PEX7 (1-240) is suitable for use in Western Blot research applications.
Clonality: Polyclonal
Conjugation: Unconjugated
Isotype: IgG
Formulation: PBS with 0.02% Sodium Azide, 50% Glycerol, pH7.3.
Purification: Affinity purification
Dilution Range: WB 1:500-1:2000
Storage Instruction: Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.
Gene Symbol: PEX7
Gene ID: 5191
Uniprot ID: PEX7_HUMAN
Immunogen Region: 1-240
Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 1-240 of human PEX7 (NP_000279.1).
Immunogen Sequence: MSAVCGGAARMLRTPGRHGY AAEFSPYLPGRLACATAQHY GIAGCGTLLILDPDEAGLRL FRSFDWNDGLFDVTWSENNE HVLITCSGDGSLQLWDTAKA AGPLQVYKEHAQEVYSVDWS QTRGEQLVVSGSWDQTVKLW DPTVGKSLCTFRGHESIIYS TIWSPHIPGCFASASGDQTL RIWDVKAAGVRIVIPAHQAE ILSCDWCKYNENLLVTGAVD CSLRGWDLRNVRQPVFELL
Tissue Specificity Ubiquitous. Highest expression in pancreas, skeletal muscle and heart.
Function Receptor required for the peroxisomal import of proteins containing a C-terminal PTS2-type peroxisomal targeting signal. Specifically binds to cargo proteins containing a PTS2 peroxisomal targeting signal in the cytosol. Cargo protein-binding triggers interaction with PEX5 and formation of a ternary complex composed of PEX5 and PEX7 along with PTS2-containing cargo proteins, which is tranlocated into peroxisomes by passing through the PEX13-PEX14 docking complex.
Protein Name Peroxisomal Targeting Signal 2 Receptor
Pts2 Receptor
Peroxin-7
Database Links Reactome: R-HSA-9033241
Cellular Localisation Cytoplasm
Cytosol
Peroxisome Matrix
Translocated Into The Peroxisome Matrix Together With Pts2-Containing Cargo Proteins And Pex5
Alternative Antibody Names Anti-Peroxisomal Targeting Signal 2 Receptor antibody
Anti-Pts2 Receptor antibody
Anti-Peroxin-7 antibody
Anti-PEX7 antibody
Anti-PTS2R antibody

Information sourced from Uniprot.org

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