| Host: |
Rabbit |
| Applications: |
WB/ELISA |
| Reactivity: |
Human/Mouse/Rat |
| Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Clonality: |
Polyclonal |
| Conjugation: |
Unconjugated |
| Isotype: |
IgG |
| Formulation: |
PBS with 0.02% Sodium Azide, 50% Glycerol, pH 7.3. |
| Purification: |
Affinity purification |
| Concentration: |
Lot specific |
| Dilution Range: |
WB:1:500-1:2000ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Storage Instruction: |
Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: |
PEX7 |
| Gene ID: |
5191 |
| Uniprot ID: |
PEX7_HUMAN |
| Immunogen Region: |
1-240 |
| Specificity: |
Recombinant fusion protein containing a sequence corresponding to amino acids 1-240 of human PEX7 (NP_000279.1). |
| Immunogen Sequence: |
MSAVCGGAARMLRTPGRHGY AAEFSPYLPGRLACATAQHY GIAGCGTLLILDPDEAGLRL FRSFDWNDGLFDVTWSENNE HVLITCSGDGSLQLWDTAKA AGPLQVYKEHAQEVYSVDWS QTRGEQLVVSGSWDQTVKLW DPTVGKSLCTFRGHESIIYS TIWSPHIPGCFASASGDQTL RIWDVKAAGVRIVIPAHQAE ILSCDWCKYNENLLVTGAVD CSLRGWDLRNVRQPVFELL |
| Tissue Specificity | Ubiquitous. Highest expression in pancreas, skeletal muscle and heart. |
| Function | Receptor required for the peroxisomal import of proteins containing a C-terminal PTS2-type peroxisomal targeting signal. Specifically binds to cargo proteins containing a PTS2 peroxisomal targeting signal in the cytosol. Cargo protein-binding triggers interaction with PEX5 and formation of a ternary complex composed of PEX5 and PEX7 along with PTS2-containing cargo proteins, which is tranlocated into peroxisomes by passing through the PEX13-PEX14 docking complex. |
| Protein Name | Peroxisomal Targeting Signal 2 ReceptorPts2 ReceptorPeroxin-7 |
| Database Links | Reactome: R-HSA-9033241 |
| Cellular Localisation | CytoplasmCytosolPeroxisome MatrixTranslocated Into The Peroxisome Matrix Together With Pts2-Containing Cargo Proteins And Pex5 |
| Alternative Antibody Names | Anti-Peroxisomal Targeting Signal 2 Receptor antibodyAnti-Pts2 Receptor antibodyAnti-Peroxin-7 antibodyAnti-PEX7 antibodyAnti-PTS2R antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
