• Western blot analysis of lysates from A-375 cells, using PDSS2 Rabbit polyclonal antibody (STJ118984) at 1:1000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (STJS000856) at 1:10000 dilution. Lysates/proteins: 25 Mu g per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit. Exposure time: 1s.

Anti-PDSS2 antibody (220-399) (STJ118984)

SKU:
STJ118984

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Host: Rabbit
Applications: WB
Reactivity: Human
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description: Rabbit polyclonal antibody anti-PDSS2 (220-399) is suitable for use in Western Blot research applications.
Clonality: Polyclonal
Conjugation: Unconjugated
Isotype: IgG
Formulation: PBS with 0.01% Thimerosal, 50% Glycerol, pH7.3.
Purification: Affinity purification
Dilution Range: WB 1:500-1:2000
Storage Instruction: Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.
Gene Symbol: PDSS2
Gene ID: 57107
Uniprot ID: DLP1_HUMAN
Immunogen Region: 220-399
Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 220-399 of human PDSS2 (NP_065114.3).
Immunogen Sequence: MDLVQGVYHENSTSKESYIT DDIGISTWKEQTFLSHGALL AKSCQAAMELAKHDAEVQNM AFQYGKHMAMSHKINSDVQP FIKEKTSDSMTFNLNSAPVV LHQEFLGRDLWIKQIGEAQE KGRLDYAKLRERIKAGKGVT SAIDLCRYHGNKALEALESF PPSEARSALENIVFAVTRFS
Function Heterotetrameric enzyme that catalyzes the condensation of farnesyl diphosphate (FPP), which acts as a primer, and isopentenyl diphosphate (IPP) to produce prenyl diphosphates of varying chain lengths and participates in the determination of the side chain of ubiquinone. Supplies nona and decaprenyl diphosphate, the precursors for the side chain of the isoprenoid quinones ubiquinone-9 (Q9) and ubiquinone-10 (Q10) respectively. The enzyme adds isopentenyl diphosphate molecules sequentially to farnesyl diphosphate with trans stereochemistry. May play a role during cerebellar development. May regulate mitochondrial respiratory chain function.
Protein Name All Trans-Polyprenyl-Diphosphate Synthase Pdss2
All-Trans-Decaprenyl-Diphosphate Synthase Subunit 2
Candidate Tumor Suppressor Protein
Decaprenyl Pyrophosphate Synthase Subunit 2
Decaprenyl-Diphosphate Synthase Subunit 2
Solanesyl-Diphosphate Synthase Subunit 2
Database Links Reactome: R-HSA-2142789
Cellular Localisation Mitochondrion
Alternative Antibody Names Anti-All Trans-Polyprenyl-Diphosphate Synthase Pdss2 antibody
Anti-All-Trans-Decaprenyl-Diphosphate Synthase Subunit 2 antibody
Anti-Candidate Tumor Suppressor Protein antibody
Anti-Decaprenyl Pyrophosphate Synthase Subunit 2 antibody
Anti-Decaprenyl-Diphosphate Synthase Subunit 2 antibody
Anti-Solanesyl-Diphosphate Synthase Subunit 2 antibody
Anti-PDSS2 antibody
Anti-C6orf210 antibody
Anti-DLP1 antibody

Information sourced from Uniprot.org

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