| Host: |
Rabbit |
| Applications: |
WB |
| Reactivity: |
Human/Mouse |
| Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description: |
Rabbit polyclonal antibody anti-PDLIM7 (90-190) is suitable for use in Western Blot research applications. |
| Clonality: |
Polyclonal |
| Conjugation: |
Unconjugated |
| Isotype: |
IgG |
| Formulation: |
PBS with 0.01% Thimerosal, 50% Glycerol, pH7.3. |
| Purification: |
Affinity purification |
| Dilution Range: |
WB 1:500-1:2000 |
| Storage Instruction: |
Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: |
PDLIM7 |
| Gene ID: |
9260 |
| Uniprot ID: |
PDLI7_HUMAN |
| Immunogen Region: |
90-190 |
| Immunogen: |
Recombinant fusion protein containing a sequence corresponding to amino acids 90-190 of human PDLIM7 (NP_998801.1). |
| Immunogen Sequence: |
KPQKASAPAADPPRYTFAPS VSLNKTARPFGAPPPADSAP QQNGQPLRPLVPDASKQRLM ENTEDWRPRPGTGQSRSFRI LAHLTGTEFMQDPDEEHLKK S |
| Tissue Specificity | Isoform 1 and isoform 2 are expressed ubiquitously, however, isoform 2 predominates in skeletal muscle, isoform 1 is more abundant in lung, spleen, leukocytes and fetal liver. |
| Function | May function as a scaffold on which the coordinated assembly of proteins can occur. May play a role as an adapter that, via its PDZ domain, localizes LIM-binding proteins to actin filaments of both skeletal muscle and nonmuscle tissues. Involved in both of the two fundamental mechanisms of bone formation, direct bone formation (e.g. embryonic flat bones mandible and cranium), and endochondral bone formation (e.g. embryonic long bone development). Plays a role during fracture repair. Involved in BMP6 signaling pathway. |
| Protein Name | Pdz And Lim Domain Protein 7Lim Mineralization ProteinLmpProtein Enigma |
| Database Links | Reactome: R-HSA-8853659 |
| Cellular Localisation | CytoplasmCytoskeletonColocalizes With Ret To The Cell Periphery And In Some Cytoskeletal ComponentsColocalizes With Tpm2 Near The Z Line In MuscleColocalizes With Tbx4 And Tbx5 To Actin Filaments |
| Alternative Antibody Names | Anti-Pdz And Lim Domain Protein 7 antibodyAnti-Lim Mineralization Protein antibodyAnti-Lmp antibodyAnti-Protein Enigma antibodyAnti-PDLIM7 antibodyAnti-ENIGMA antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
