| Host: |
Rabbit |
| Applications: |
WB |
| Reactivity: |
Mouse/Rat |
| Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description: |
Rabbit polyclonal antibody anti-PAQR8 (1-75) is suitable for use in Western Blot research applications. |
| Clonality: |
Polyclonal |
| Conjugation: |
Unconjugated |
| Isotype: |
IgG |
| Formulation: |
PBS with 0.01% Thimerosal, 50% Glycerol, pH7.3. |
| Purification: |
Affinity purification |
| Dilution Range: |
WB 1:500-1:2000 |
| Storage Instruction: |
Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: |
PAQR8 |
| Gene ID: |
85315 |
| Uniprot ID: |
PAQR8_HUMAN |
| Immunogen Region: |
1-75 |
| Immunogen: |
Recombinant fusion protein containing a sequence corresponding to amino acids 1-75 of human PAQR8 (NP_588608.1). |
| Immunogen Sequence: |
MTTAILERLSTLSVSGQQLR RLPKILEDGLPKMPCTVPET DVPQLFREPYIRTGYRPTGH EWRYYFFSLFQKHNE |
| Tissue Specificity | Highly expressed in the hypothalamus. Also expressed in spinal cord, kidney and testis. |
| Function | Plasma membrane progesterone (P4) receptor coupled to G proteins. Seems to act through a G(i) mediated pathway. May be involved in oocyte maturation. Also binds dehydroepiandrosterone (DHEA), pregnanolone, pregnenolone and allopregnanolone. |
| Protein Name | Membrane Progestin Receptor BetaMpr BetaLysosomal Membrane Protein In Brain 1Membrane Progesterone P4 Receptor BetaMembrane Progesterone Receptor BetaProgesterone And Adipoq Receptor Family Member 8Progestin And Adipoq Receptor Family Member 8Progestin And Adipoq Receptor Family Member Viii |
| Cellular Localisation | Cell MembraneMulti-Pass Membrane ProteinColocalizes With A Lysosomal Protein Ctsd/Cathepsin D |
| Alternative Antibody Names | Anti-Membrane Progestin Receptor Beta antibodyAnti-Mpr Beta antibodyAnti-Lysosomal Membrane Protein In Brain 1 antibodyAnti-Membrane Progesterone P4 Receptor Beta antibodyAnti-Membrane Progesterone Receptor Beta antibodyAnti-Progesterone And Adipoq Receptor Family Member 8 antibodyAnti-Progestin And Adipoq Receptor Family Member 8 antibodyAnti-Progestin And Adipoq Receptor Family Member Viii antibodyAnti-PAQR8 antibodyAnti-C6orf33 antibodyAnti-LMPB1 antibodyAnti-MPRB antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
