| Background | The product of this gene belongs to the family of G-protein coupled receptors. This family has several receptor subtypes with different pharmacological selectivity, which overlaps in some cases, for various adenosine and uridine nucleotides. This receptor functions as a receptor for extracellular ATP and ADP. In platelets binding to ADP leads to mobilization of intracellular calcium ions via activation of phospholipase C, a change in platelet shape, and probably to platelet aggregation. |
| Function | Receptor for extracellular adenine nucleotides such as ADP. In platelets, binding to ADP leads to mobilization of intracellular calcium ions via activation of phospholipase C, a change in platelet shape, and ultimately platelet aggregation. |
| Database Links | Reactome: R-HSA-416476 |
| Cellular Localisation | Cell MembraneMulti-Pass Membrane Protein |
| Protein Name | P2y Purinoceptor 1P2y1Adp ReceptorPurinergic Receptor |
| Alternative Names | Anti-P2y Purinoceptor 1 antibodyAnti-P2y1 antibodyAnti-Adp Receptor antibodyAnti-Purinergic Receptor antibodyAnti-P2RY1 antibody |
Information sourced from uniprot.org
