• Western blot analysis of various lysates, using p16 INK4A Rabbit polyclonal antibody (STJ11105241) at 1:1000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (STJS000856) at 1:10000 dilution. Lysates/proteins: 25ug per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit. Exposure time: 45s.

Anti-p16 INK4A antibody (STJ11105241)

SKU:
STJ11105241

€140.63 - €653.13
Current Stock:
Host: Rabbit
Applications: WB
Reactivity: Human/Mouse/Rat
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description: Rabbit polyclonal antibody anti-p16 INK4A is suitable for use in Western Blot research applications.
Clonality: Polyclonal
Conjugation: Unconjugated
Isotype: IgG
Formulation: PBS with 0.05% Proclin300, 50% Glycerol, pH7.3.
Purification: Affinity purification
Dilution Range: WB 1:500-1:1000
Storage Instruction: Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.
Gene Symbol: Cdkn2a
Gene ID: 12578
Uniprot ID: CDN2A_MOUSE
Immunogen: Recombinant protein of mouse p16 INK4A.
Post Translational Modifications Phosphorylation seems to increase interaction with CDK4.
Function Acts as a negative regulator of the proliferation of normal cells by interacting strongly with CDK4 and CDK6. This inhibits their ability to interact with cyclins D and to phosphorylate the retinoblastoma protein.
Protein Name Cyclin-Dependent Kinase Inhibitor 2a
Cyclin-Dependent Kinase 4 Inhibitor A
Cdk4i
P16-Ink4a
P16-Ink4
Cellular Localisation Cytoplasm
Nucleus
Alternative Antibody Names Anti-Cyclin-Dependent Kinase Inhibitor 2a antibody
Anti-Cyclin-Dependent Kinase 4 Inhibitor A antibody
Anti-Cdk4i antibody
Anti-P16-Ink4a antibody
Anti-P16-Ink4 antibody
Anti-Cdkn2a antibody
Anti-P16ink4a antibody

Information sourced from Uniprot.org

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