Anti-OASL antibody (315-514) (STJ112547)

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STJ112547
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Host: Rabbit
Applications: WB/ELISA
Reactivity: Human
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Clonality : Polyclonal
Conjugation: Unconjugated
Isotype: IgG
Formulation: PBS with 0.02% Sodium Azide, 50% Glycerol, pH 7.3.
Purification: Affinity purification
Concentration: Lot specific
Dilution Range: WB:1:200-1:1000
ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements.
Storage Instruction: Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.
Gene Symbol: OASL
Gene ID: 8638
Uniprot ID: OASL_HUMAN
Immunogen Region: 315-514
Specificity: Recombinant fusion protein containing a sequence corresponding to amino acids 315-514 of human OASL (NP_003724.1).
Immunogen Sequence: EGYRWDIVAQRASQCLKQDC CYDNRENPISSWNVKRARDI HLTVEQRGYPDFNLIVNPYE PIRKVKEKIRRTRGYSGLQR LSFQVPGSERQLLSSRCSLA KYGIFSHTHIYLLETIPSEI QVFVKNPDGGSYAYAINPNS FILGLKQQIEDQQGLPKKQQ QLEFQGQVLQDWLGLGIYGI QDSDTLILSKKKGEALFPAS
Tissue Specificity Expressed in most tissues, with the highest levels in primary blood Leukocytes and other hematopoietic system tissues, colon, stomach and to some extent in testis.
Function Does not have 2'-5'-OAS activity, but can bind double-stranded RNA. Displays antiviral activity against encephalomyocarditis virus (EMCV) and hepatitis C virus (HCV) via an alternative antiviral pathway independent of RNase L.
Protein Name 2'-5'-Oligoadenylate Synthase-Like Protein
2'-5'-Oas-Related Protein
2'-5'-Oas-Rp
59 Kda 2'-5'-Oligoadenylate Synthase-Like Protein
Thyroid Receptor-Interacting Protein 14
Tr-Interacting Protein 14
Trip-14
P59 Oasl
P59oasl
Database Links Reactome: R-HSA-877300
Reactome: R-HSA-8983711
Reactome: R-HSA-909733
Cellular Localisation Isoform P56: Nucleus
Nucleolus
Cytoplasm
Isoform P30: Cytoplasm
Alternative Antibody Names Anti-2'-5'-Oligoadenylate Synthase-Like Protein antibody
Anti-2'-5'-Oas-Related Protein antibody
Anti-2'-5'-Oas-Rp antibody
Anti-59 Kda 2'-5'-Oligoadenylate Synthase-Like Protein antibody
Anti-Thyroid Receptor-Interacting Protein 14 antibody
Anti-Tr-Interacting Protein 14 antibody
Anti-Trip-14 antibody
Anti-P59 Oasl antibody
Anti-P59oasl antibody
Anti-OASL antibody
Anti-TRIP14 antibody

Information sourced from Uniprot.org