| Host: |
Rabbit |
| Applications: |
WB |
| Reactivity: |
Human |
| Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description: |
Rabbit polyclonal antibody anti-OASL (315-514) is suitable for use in Western Blot research applications. |
| Clonality: |
Polyclonal |
| Conjugation: |
Unconjugated |
| Isotype: |
IgG |
| Formulation: |
PBS with 0.02% Sodium Azide, 50% Glycerol, pH7.3. |
| Purification: |
Affinity purification |
| Dilution Range: |
WB 1:200-1:1000 |
| Storage Instruction: |
Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: |
OASL |
| Gene ID: |
8638 |
| Uniprot ID: |
OASL_HUMAN |
| Immunogen Region: |
315-514 |
| Immunogen: |
Recombinant fusion protein containing a sequence corresponding to amino acids 315-514 of human OASL (NP_003724.1). |
| Immunogen Sequence: |
EGYRWDIVAQRASQCLKQDC CYDNRENPISSWNVKRARDI HLTVEQRGYPDFNLIVNPYE PIRKVKEKIRRTRGYSGLQR LSFQVPGSERQLLSSRCSLA KYGIFSHTHIYLLETIPSEI QVFVKNPDGGSYAYAINPNS FILGLKQQIEDQQGLPKKQQ QLEFQGQVLQDWLGLGIYGI QDSDTLILSKKKGEALFPAS |
| Tissue Specificity | Expressed in most tissues, with the highest levels in primary blood Leukocytes and other hematopoietic system tissues, colon, stomach and to some extent in testis. |
| Function | Does not have 2'-5'-OAS activity, but can bind double-stranded RNA. Displays antiviral activity against encephalomyocarditis virus (EMCV) and hepatitis C virus (HCV) via an alternative antiviral pathway independent of RNase L. |
| Protein Name | 2'-5'-Oligoadenylate Synthase-Like Protein2'-5'-Oas-Related Protein2'-5'-Oas-Rp59 Kda 2'-5'-Oligoadenylate Synthase-Like ProteinThyroid Receptor-Interacting Protein 14Tr-Interacting Protein 14Trip-14P59 OaslP59oasl |
| Database Links | Reactome: R-HSA-877300Reactome: R-HSA-8983711Reactome: R-HSA-909733 |
| Cellular Localisation | Isoform P56: NucleusNucleolusCytoplasmIsoform P30: Cytoplasm |
| Alternative Antibody Names | Anti-2'-5'-Oligoadenylate Synthase-Like Protein antibodyAnti-2'-5'-Oas-Related Protein antibodyAnti-2'-5'-Oas-Rp antibodyAnti-59 Kda 2'-5'-Oligoadenylate Synthase-Like Protein antibodyAnti-Thyroid Receptor-Interacting Protein 14 antibodyAnti-Tr-Interacting Protein 14 antibodyAnti-Trip-14 antibodyAnti-P59 Oasl antibodyAnti-P59oasl antibodyAnti-OASL antibodyAnti-TRIP14 antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
