| Host: |
Rabbit |
| Applications: |
WB |
| Reactivity: |
Mouse |
| Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description: |
Rabbit polyclonal antibody anti-NUBP1 (201-320) is suitable for use in Western Blot research applications. |
| Clonality: |
Polyclonal |
| Conjugation: |
Unconjugated |
| Isotype: |
IgG |
| Formulation: |
PBS with 0.01% Thimerosal, 50% Glycerol, pH7.3. |
| Purification: |
Affinity purification |
| Dilution Range: |
WB 1:500-1:2000 |
| Storage Instruction: |
Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: |
NUBP1 |
| Gene ID: |
4682 |
| Uniprot ID: |
NUBP1_HUMAN |
| Immunogen Region: |
201-320 |
| Immunogen: |
Recombinant fusion protein containing a sequence corresponding to amino acids 201-320 of human NUBP1 (NP_002475.2). |
| Immunogen Sequence: |
PQEVSLQDVRKEINFCRKVK LPIIGVVENMSGFICPKCKK ESQIFPPTTGGAELMCQDLE VPLLGRVPLDPLIGKNCDKG QSFFIDAPDSPATLAYRSII QRIQEFCNLHQSKEENLISS |
| Function | Component of the cytosolic iron-sulfur (Fe/S) protein assembly (CIA) machinery. Required for maturation of extramitochondrial Fe-S proteins. The NUBP1-NUBP2 heterotetramer forms a Fe-S scaffold complex, mediating the de novo assembly of an Fe-S cluster and its transfer to target apoproteins. Implicated in the regulation of centrosome duplication. Negatively regulates cilium formation and structure. |
| Protein Name | Cytosolic Fe-S Cluster Assembly Factor Nubp1Nucleotide-Binding Protein 1Nbp 1 |
| Database Links | Reactome: R-HSA-2564830 |
| Cellular Localisation | CytoplasmNucleusCell ProjectionCytoskeletonCilium AxonemeCilium Basal BodyMicrotubule Organizing CenterCentrosomeCentrioleEnriched In Centrioles Of Microtubule Asters During ProphasePrometaphase And Telophase Stages Of MitosisLocalized At Centrioles And In The Nucleus At InterphaseColocalizes With Nubp-2 At PrometaphaseSpecifically Localizes To The Axenome Of Motile Cilia As Opposed To Primary Non-Motile CiliaLocalization Is Independent Of Nubp2 And Kifc1 |
| Alternative Antibody Names | Anti-Cytosolic Fe-S Cluster Assembly Factor Nubp1 antibodyAnti-Nucleotide-Binding Protein 1 antibodyAnti-Nbp 1 antibodyAnti-NUBP1 antibodyAnti-NBP antibodyAnti-NBP1 antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
