| Host: |
Rabbit |
| Applications: |
IHC |
| Reactivity: |
Human/Mouse/Rat |
| Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description: |
Rabbit polyclonal antibody anti-NMT1 (1-250) is suitable for use in Immunohistochemistry research applications. |
| Clonality: |
Polyclonal |
| Conjugation: |
Unconjugated |
| Isotype: |
IgG |
| Formulation: |
PBS with 0.02% Sodium Azide, 50% Glycerol, pH7.3. |
| Purification: |
Affinity purification |
| Dilution Range: |
IHC-P 1:50-1:200 |
| Storage Instruction: |
Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: |
NMT1 |
| Gene ID: |
4836 |
| Uniprot ID: |
NMT1_HUMAN |
| Immunogen Region: |
1-250 |
| Immunogen: |
Recombinant fusion protein containing a sequence corresponding to amino acids 1-250 of human NMT1 (NP_066565.1). |
| Immunogen Sequence: |
MADESETAVKPPAPPLPQMM EGNGNGHEHCSDCENEEDNS YNRGGLSPANDTGAKKKKKK QKKKKEKGSETDSAQDQPVK MNSLPAERIQEIQKAIELFS VGQGPAKTMEEASKRSYQFW DTQPVPKLGEVVNTHGPVEP DKDNIRQEPYTLPQGFTWDA LDLGDRGVLKELYTLLNENY VEDDDNMFRFDYSPEFLLWA LRPPGWLPQWHCGVRVVSSR KLVGFISAIPANIHIYDTE |
| Tissue Specificity | Heart, gut, kidney, liver and placenta. |
| Function | Adds a myristoyl group to the N-terminal glycine residue of certain cellular and viral proteins. Also able to mediate N-terminal lysine myristoylation of proteins: catalyzes myristoylation of ARF6 on both 'Gly-2' and 'Lys-3'. Lysine myristoylation is required to maintain ARF6 on membranes during the GTPase cycle. |
| Protein Name | Glycylpeptide N-Tetradecanoyltransferase 1Myristoyl-Coa -Protein N-Myristoyltransferase 1Hsnmt1Nmt 1Type I N-MyristoyltransferasePeptide N-Myristoyltransferase 1Protein-Lysine Myristoyltransferase Nmt1 |
| Database Links | Reactome: R-HSA-162599Reactome: R-HSA-2514859Reactome: R-HSA-75108 |
| Cellular Localisation | CytoplasmCytosolMembranePeripheral Membrane ProteinCopurifies With Ribosomes |
| Alternative Antibody Names | Anti-Glycylpeptide N-Tetradecanoyltransferase 1 antibodyAnti-Myristoyl-Coa -Protein N-Myristoyltransferase 1 antibodyAnti-Hsnmt1 antibodyAnti-Nmt 1 antibodyAnti-Type I N-Myristoyltransferase antibodyAnti-Peptide N-Myristoyltransferase 1 antibodyAnti-Protein-Lysine Myristoyltransferase Nmt1 antibodyAnti-NMT1 antibodyAnti-NMT antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
