| Host: |
Rabbit |
| Applications: |
WB |
| Reactivity: |
Human |
| Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description: |
Rabbit polyclonal antibody anti-NFRKB (1-340) is suitable for use in Western Blot research applications. |
| Clonality: |
Polyclonal |
| Conjugation: |
Unconjugated |
| Isotype: |
IgG |
| Formulation: |
PBS with 0.02% Sodium Azide, 50% Glycerol, pH7.3. |
| Purification: |
Affinity purification |
| Dilution Range: |
WB 1:500-1:2000 |
| Storage Instruction: |
Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: |
NFRKB |
| Gene ID: |
4798 |
| Uniprot ID: |
NFRKB_HUMAN |
| Immunogen Region: |
1-340 |
| Immunogen: |
Recombinant fusion protein containing a sequence corresponding to amino acids 1-340 of human NFRKB (NP_001137307.1). |
| Immunogen Sequence: |
MDSLDHMLTDPLELGPCGDG HGTRIMEDCLLGGTRVSLPE DLLEDPEIFFDVVSLSTWQE VLSDSQREHLQQFLPQFPED SAEQQNELILALFSGENFRF GNPLHIAQKLFRDGHFNPEV VKYRQLCFKSQYKRYLNSQQ QYFHRLLKQILASRSDLLEM ARRSGPALPFRQKRPSPSRT PEEREWRTQQRYLKVLREVK EECGDTALSSDEEDLSSWLP SSPARSPSPAVPLRVVPTL |
| Tissue Specificity | Expressed in thymus, brain, testes, spleen and liver. |
| Function | Binds to the DNA consensus sequence 5'-GGGGAATCTCC-3'. Putative regulatory component of the chromatin remodeling INO80 complex which is involved in transcriptional regulation, DNA replication and probably DNA repair. Modulates the deubiquitinase activity of UCHL5 in the INO80 complex. |
| Protein Name | Nuclear Factor Related To Kappa-B-Binding ProteinDna-Binding Protein R Kappa-BIno80 Complex Subunit G |
| Database Links | Reactome: R-HSA-5689603Reactome: R-HSA-5696394 |
| Cellular Localisation | Nucleus |
| Alternative Antibody Names | Anti-Nuclear Factor Related To Kappa-B-Binding Protein antibodyAnti-Dna-Binding Protein R Kappa-B antibodyAnti-Ino80 Complex Subunit G antibodyAnti-NFRKB antibodyAnti-INO80G antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
