Host: |
Rabbit |
Applications: |
WB |
Reactivity: |
Human/Mouse/Rat |
Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Short Description: |
Rabbit polyclonal antibody anti-NEURL2 (181-285) is suitable for use in Western Blot research applications. |
Clonality: |
Polyclonal |
Conjugation: |
Unconjugated |
Isotype: |
IgG |
Formulation: |
PBS with 0.01% Thimerosal, 50% Glycerol, pH7.3. |
Purification: |
Affinity purification |
Dilution Range: |
WB 1:500-1:2000 |
Storage Instruction: |
Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Gene Symbol: |
NEURL2 |
Gene ID: |
140825 |
Uniprot ID: |
NEUL2_HUMAN |
Immunogen Region: |
181-285 |
Immunogen: |
Recombinant fusion protein containing a sequence corresponding to amino acids 181-285 of human NEURL2 (NP_542787.1). |
Immunogen Sequence: |
LPPTARRSRLGVLFCPRPDG TADMHIIINGEDMGPSARGL PAAQPLYAVVDVFASTKSVR LVQLEYGLPSLQTLCRLVIQ RSMVHRLAIDGLHLPKELKD FCKYE |
Tissue Specificity | Expressed specifically in skeletal and cardiac muscles. |
Function | Plays an important role in the process of myofiber differentiation and maturation. Probable substrate-recognition component of a SCF-like ECS (Elongin BC-CUL2/5-SOCS-box protein) E3 ubiquitin-protein ligase complex, which mediates the ubiquitination of proteins. Probably contributes to catalysis through recognition and positioning of the substrate and the ubiquitin-conjugating enzyme. During myogenesis, controls the ubiquitination and degradation of the specific pool of CTNNB1/beta-catenin located at the sarcolemma. |
Protein Name | Neuralized-Like Protein 2 |
Database Links | Reactome: R-HSA-8951664 |
Cellular Localisation | Cytoplasm |
Alternative Antibody Names | Anti-Neuralized-Like Protein 2 antibodyAnti-NEURL2 antibodyAnti-C20orf163 antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance