Anti-MYOZ1 antibody (180-299 aa) (STJ11106125)

SKU:
STJ11106125
€140.63 - €655.63
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Host: Rabbit
Applications: WB/ELISA
Reactivity: Mouse/Rat
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Clonality : Polyclonal
Conjugation: Unconjugated
Isotype: IgG
Formulation: PBS with 0.01% Thimerosal, 50% Glycerol, pH 7.3.
Purification: Affinity purification
Concentration: Lot specific
Dilution Range: WB:1:500-1:2000
ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements.
Gene Symbol: MYOZ1
Gene ID: 58529
Uniprot ID: MYOZ1_HUMAN
Immunogen Region: 180-299 aa
Specificity: Recombinant fusion protein containing a sequence corresponding to amino acids 180-299 of human MYOZ1 (NP_067068.1).
Immunogen Sequence: VFKTYISPWERAMGVDPQQK MELGIDLLAYGAKAELPKYK SFNRTAMPYGGYEKASKRMT FQMPKFDLGPLLSEPLVLYN QNLSNRPSFNRTPIPWLSSG EPVDYNVDIGIPLDGETEEL
Tissue Specificity Expressed primarily in skeletal muscle. Detected at lower levels in heart, prostate and pancreas.
Function Myozenins may serve as intracellular binding proteins involved in linking Z-disk proteins such as alpha-actinin, gamma-filamin, TCAP/telethonin, LDB3/ZASP and localizing calcineurin signaling to the sarcomere. Plays an important role in the modulation of calcineurin signaling. May play a role in myofibrillogenesis.
Protein Name Myozenin-1
Calsarcin-2
Filamin- - Actinin- And Telethonin-Binding Protein
Protein Fatz
Cellular Localisation Nucleus
Cell Projection
Pseudopodium
Localized To The Nucleus And Pseudopodia Of Undifferentiated Cells And Detected Throughout The Myotubes Of Differentiated Cells
Colocalizes With Actn2
Flnc And Myot At The Z-Lines Of Skeletal Muscle
Alternative Antibody Names Anti-Myozenin-1 antibody
Anti-Calsarcin-2 antibody
Anti-Filamin- - Actinin- And Telethonin-Binding Protein antibody
Anti-Protein Fatz antibody
Anti-MYOZ1 antibody
Anti-MYOZ antibody

Information sourced from Uniprot.org