| Tissue Specificity | Ubiquitous, with stronger expression in tissues with high energy requirements: heart, brain, and skeletal muscle. |
| Function | Polymerase that creates the 3' poly(A) tail of mitochondrial transcripts. Can use all four nucleotides, but has higher activity with ATP and UTP (in vitro). Plays a role in replication-dependent histone mRNA degradation. May be involved in the terminal uridylation of mature histone mRNAs before their degradation is initiated. Might be responsible for the creation of some UAA stop codons which are not encoded in mtDNA. |
| Protein Name | Poly(A Rna Polymerase - MitochondrialPapPap-Associated Domain-Containing Protein 1Polynucleotide AdenylyltransferaseTerminal Uridylyltransferase 1Tutase 1Mtpap |
| Cellular Localisation | CytoplasmMitochondrion |
| Alternative Antibody Names | Anti-Poly(A Rna Polymerase - Mitochondrial antibodyAnti-Pap antibodyAnti-Pap-Associated Domain-Containing Protein 1 antibodyAnti-Polynucleotide Adenylyltransferase antibodyAnti-Terminal Uridylyltransferase 1 antibodyAnti-Tutase 1 antibodyAnti-Mtpap antibodyAnti-MTPAP antibodyAnti-PAPD1 antibody |
Information sourced from Uniprot.org
