• Chromatin immunoprecipitation analysis of extracts of HeLa cells, using MTA2 antibody (STJ24625) and rabbit IgG. The amount of immunoprecipitated DNA was checked by quantitative PCR. Histogram was constructed by the ratios of the immunoprecipitated DNA to the input.
  • Western blot analysis of lysates from wild type (WT) and MTA2 knockout (KO) 293T cells, using [KO Validated] MTA2 Rabbit polyclonal antibody (STJ24625) at 1:1000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (STJS000856) at 1:10000 dilution. Lysates/proteins: 25 Mu g per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit. Exposure time: 1s.

Anti-MTA2 antibody (60-180) (STJ24625)

SKU:
STJ24625

£129.50 - £642.50
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Host: Rabbit
Applications: WB/ELISA/ChIP
Reactivity: Human/Mouse/Rat
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Clonality: Polyclonal
Conjugation: Unconjugated
Isotype: IgG
Formulation: PBS with 0.01% Thimerosal, 50% Glycerol, pH 7.3.
Purification: Affinity purification
Concentration: Lot specific
Dilution Range: WB:1:500-1:1000
ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements.
ChIP:5 Mu g antibody for 10 Mu g-15 Mu g of Chromatin
Storage Instruction: Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.
Gene Symbol: MTA2
Gene ID: 9219
Uniprot ID: MTA2_HUMAN
Immunogen Region: 60-180
Specificity: Recombinant fusion protein containing a sequence corresponding to amino acids 60-180 of human MTA2 (NP_004730.2).
Immunogen Sequence: DSNAREFEEESKQPGVSEQQ RHQLKHRELFLSRQFESLPA THIRGKCSVTLLNETDILSQ YLEKEDCFFYSLVFDPVQKT LLADQGEIRVGCKYQAEIPD RLVEGESDNRNQQKMEMKVW D
Tissue Specificity Widely expressed.
Function May function as a transcriptional coregulator. Acts as a component of the histone deacetylase NuRD complex which participates in the remodeling of chromatin.
Protein Name Metastasis-Associated Protein Mta2
Metastasis-Associated 1-Like 1
Mta1-L1 Protein
P53 Target Protein In Deacetylase Complex
Database Links Reactome: R-HSA-3214815
Reactome: R-HSA-427389
Reactome: R-HSA-6804758
Reactome: R-HSA-73762
Reactome: R-HSA-8943724
Reactome: R-HSA-9679191
Reactome: R-HSA-9843940
Reactome: R-HSA-9844594
Reactome: R-HSA-9845323
Cellular Localisation Nucleus
Alternative Antibody Names Anti-Metastasis-Associated Protein Mta2 antibody
Anti-Metastasis-Associated 1-Like 1 antibody
Anti-Mta1-L1 Protein antibody
Anti-P53 Target Protein In Deacetylase Complex antibody
Anti-MTA2 antibody
Anti-MTA1L1 antibody
Anti-PID antibody

Information sourced from Uniprot.org

12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance