Host: |
Rabbit |
Applications: |
WB |
Reactivity: |
Mouse |
Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Short Description: |
Rabbit polyclonal antibody anti-MPP7 (297-576) is suitable for use in Western Blot research applications. |
Clonality: |
Polyclonal |
Conjugation: |
Unconjugated |
Isotype: |
IgG |
Formulation: |
PBS with 0.01% Thimerosal, 50% Glycerol, pH7.3. |
Purification: |
Affinity purification |
Dilution Range: |
WB 1:500-1:2000 |
Storage Instruction: |
Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Gene Symbol: |
MPP7 |
Gene ID: |
143098 |
Uniprot ID: |
MPP7_HUMAN |
Immunogen Region: |
297-576 |
Immunogen: |
Recombinant fusion protein containing a sequence corresponding to amino acids 297-576 of human MPP7 (NP_775767.2). |
Immunogen Sequence: |
RLALRRPEILVQPLKVSNRK SSGFRKSFRLSRKDKKTNKS MYECKKSDQYDTADVPTYEE VTPYRRQTNEKYRLVVLVGP VGVGLNELKRKLLISDTQHY GVTVPHTTRARRSQESDGVE YIFISKHLFETDVQNNKFIE YGEYKNNYYGTSIDSVRSVL AKNKVCLLDVQPHTVKHLRT LEFKPYVIFIKPPSIERLRE TRKNAKIISSRDDQGAAKPF TEEDFQEMIKSAQIMESQY |
Post Translational Modifications | Phosphorylated by aPKC which promotes dissociation from the cell cortex. |
Function | Acts as an important adapter that promotes epithelial cell polarity and tight junction formation via its interaction with DLG1. Involved in the assembly of protein complexes at sites of cell-cell contact. |
Protein Name | Maguk P55 Subfamily Member 7 |
Database Links | Reactome: R-HSA-9013149Reactome: R-HSA-9013404Reactome: R-HSA-9013406Reactome: R-HSA-9013408Reactome: R-HSA-9013409Reactome: R-HSA-9013423 |
Cellular Localisation | MembranePeripheral Membrane ProteinLateral Cell MembraneCell JunctionTight JunctionAdherens JunctionCytoplasmCell CortexIn Epidermal CellsDetected Primarily At The Lateral Cell Membrane |
Alternative Antibody Names | Anti-Maguk P55 Subfamily Member 7 antibodyAnti-MPP7 antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance