• Western blot analysis of lysates from mouse lung, using MPP7 Rabbit polyclonal antibody (STJ119025) at 1:1000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (STJS000856) at 1:10000 dilution. Lysates/proteins: 25 Mu g per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit. Exposure time: 1s.

Anti-MPP7 antibody (297-576) (STJ119025)

SKU:
STJ119025

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Host: Rabbit
Applications: WB
Reactivity: Mouse
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description: Rabbit polyclonal antibody anti-MPP7 (297-576) is suitable for use in Western Blot research applications.
Clonality: Polyclonal
Conjugation: Unconjugated
Isotype: IgG
Formulation: PBS with 0.01% Thimerosal, 50% Glycerol, pH7.3.
Purification: Affinity purification
Dilution Range: WB 1:500-1:2000
Storage Instruction: Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.
Gene Symbol: MPP7
Gene ID: 143098
Uniprot ID: MPP7_HUMAN
Immunogen Region: 297-576
Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 297-576 of human MPP7 (NP_775767.2).
Immunogen Sequence: RLALRRPEILVQPLKVSNRK SSGFRKSFRLSRKDKKTNKS MYECKKSDQYDTADVPTYEE VTPYRRQTNEKYRLVVLVGP VGVGLNELKRKLLISDTQHY GVTVPHTTRARRSQESDGVE YIFISKHLFETDVQNNKFIE YGEYKNNYYGTSIDSVRSVL AKNKVCLLDVQPHTVKHLRT LEFKPYVIFIKPPSIERLRE TRKNAKIISSRDDQGAAKPF TEEDFQEMIKSAQIMESQY
Post Translational Modifications Phosphorylated by aPKC which promotes dissociation from the cell cortex.
Function Acts as an important adapter that promotes epithelial cell polarity and tight junction formation via its interaction with DLG1. Involved in the assembly of protein complexes at sites of cell-cell contact.
Protein Name Maguk P55 Subfamily Member 7
Database Links Reactome: R-HSA-9013149
Reactome: R-HSA-9013404
Reactome: R-HSA-9013406
Reactome: R-HSA-9013408
Reactome: R-HSA-9013409
Reactome: R-HSA-9013423
Cellular Localisation Membrane
Peripheral Membrane Protein
Lateral Cell Membrane
Cell Junction
Tight Junction
Adherens Junction
Cytoplasm
Cell Cortex
In Epidermal Cells
Detected Primarily At The Lateral Cell Membrane
Alternative Antibody Names Anti-Maguk P55 Subfamily Member 7 antibody
Anti-MPP7 antibody

Information sourced from Uniprot.org

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