| Host: |
Rabbit |
| Applications: |
WB/IF |
| Reactivity: |
Human/Mouse |
| Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description: |
Rabbit polyclonal antibody anti-MPG (1-293) is suitable for use in Western Blot and Immunofluorescence research applications. |
| Clonality: |
Polyclonal |
| Conjugation: |
Unconjugated |
| Isotype: |
IgG |
| Formulation: |
PBS with 0.02% Sodium Azide, 50% Glycerol, pH7.3. |
| Purification: |
Affinity purification |
| Dilution Range: |
WB 1:500-1:2000IF/ICC 1:50-1:200 |
| Storage Instruction: |
Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: |
MPG |
| Gene ID: |
4350 |
| Uniprot ID: |
3MG_HUMAN |
| Immunogen Region: |
1-293 |
| Immunogen: |
Recombinant fusion protein containing a sequence corresponding to amino acids 1-293 of human MPG (NP_001015052.1). |
| Immunogen Sequence: |
MPARSGAQFCRRMGQKKQRP ARAGQPHSSSDAAQAPAEQP HSSSDAAQAPCPRERCLGPP TTPGPYRSIYFSSPKGHLTR LGLEFFDQPAVPLARAFLGQ VLVRRLPNGTELRGRIVETE AYLGPEDEAAHSRGGRQTPR NRGMFMKPGTLYVYIIYGMY FCMNISSQGDGACVLLRALE PLEGLETMRQLRSTLRKGTA SRVLKDRELCSGPSKLCQAL AINKSFDQRDLAQDEAVWL |
| Function | Hydrolysis of the deoxyribose N-glycosidic bond to excise 3-methyladenine, and 7-methylguanine from the damaged DNA polymer formed by alkylation lesions. |
| Protein Name | Dna-3-Methyladenine Glycosylase3-Alkyladenine Dna Glycosylase3-Methyladenine Dna GlycosidaseAdpgN-Methylpurine-Dna Glycosylase |
| Database Links | Reactome: R-HSA-110330Reactome: R-HSA-110331Reactome: R-HSA-110357 |
| Cellular Localisation | CytoplasmMitochondrion MatrixMitochondrion NucleoidNucleus |
| Alternative Antibody Names | Anti-Dna-3-Methyladenine Glycosylase antibodyAnti-3-Alkyladenine Dna Glycosylase antibodyAnti-3-Methyladenine Dna Glycosidase antibodyAnti-Adpg antibodyAnti-N-Methylpurine-Dna Glycosylase antibodyAnti-MPG antibodyAnti-AAG antibodyAnti-ANPG antibodyAnti-MID1 antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
![Western blot analysis of lysates from wild type (WT) and MPG knockout (KO) HeLa cells, using [KO Validated] MPG Rabbit polyclonal antibody (STJ11100043) at 1:1000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (STJS000856) at 1:10000 dilution. Lysates/proteins: 25 Mu g per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit. Exposure time: 60s.](https://cdn11.bigcommerce.com/s-zso2xnchw9/images/stencil/300x300/products/89115/357567/STJ11100043_1__91960.1713121694.jpg?c=1 "Western blot analysis of lysates from wild type (WT) and MPG knockout (KO) HeLa cells, using [KO Validated] MPG Rabbit polyclonal antibody (STJ11100043) at 1:1000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (STJS000856) at 1:10000 dilution. Lysates/proteins: 25 Mu g per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit. Exposure time: 60s.")
