| Host: |
Rabbit |
| Applications: |
WB/ELISA |
| Reactivity: |
Human/Mouse |
| Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Clonality: |
Polyclonal |
| Conjugation: |
Unconjugated |
| Isotype: |
IgG |
| Formulation: |
PBS with 0.01% Thimerosal, 50% Glycerol, pH 7.3. |
| Purification: |
Affinity purification |
| Concentration: |
Lot specific |
| Dilution Range: |
WB:1:500-1:2000ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Storage Instruction: |
Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: |
MLC1 |
| Gene ID: |
23209 |
| Uniprot ID: |
MLC1_HUMAN |
| Immunogen Region: |
C-Term |
| Specificity: |
A synthetic peptide corresponding to a sequence within amino acids 300 to the C-terminus of human MLC1 (NP_055981.1). |
| Immunogen Sequence: |
SYDVLLLLLLLVLLLQAGLN TGTAIQCVRFKVSARLQGAS WDTQNGPQERLAGEVARSPL KEFDKEKAWRAVVVQMAQ |
| Tissue Specificity | Expressed in the brain, with highest levels found in the amygdala, nucleus caudatus, thalamus and hippocampus. |
| Function | Transmembrane protein mainly expressed in brain atrocytes that may play a role in transport across the blood-brain and brain-cerebrospinal fluid barriers. Regulates the response of astrocytes to hypo-osmosis by promoting calcium influx. May function as regulatory protein of membrane protein complexes such as ion channels (Probable). |
| Protein Name | Membrane Protein Mlc1Megalencephalic Leukoencephalopathy With Subcortical Cysts Protein 1 |
| Cellular Localisation | MembraneMulti-Pass Membrane ProteinCell MembraneCytoplasmPerinuclear RegionEndoplasmic Reticulum |
| Alternative Antibody Names | Anti-Membrane Protein Mlc1 antibodyAnti-Megalencephalic Leukoencephalopathy With Subcortical Cysts Protein 1 antibodyAnti-MLC1 antibodyAnti-KIAA0027 antibodyAnti-WKL1 antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
