| Host: |
Rabbit |
| Applications: |
WB |
| Reactivity: |
Mouse |
| Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description: |
Rabbit polyclonal antibody anti-MICALL1 (614-863) is suitable for use in Western Blot research applications. |
| Clonality: |
Polyclonal |
| Conjugation: |
Unconjugated |
| Isotype: |
IgG |
| Formulation: |
PBS with 0.01% Thimerosal, 50% Glycerol, pH7.3. |
| Purification: |
Affinity purification |
| Dilution Range: |
WB 1:200-1:2000 |
| Storage Instruction: |
Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: |
MICALL1 |
| Gene ID: |
85377 |
| Uniprot ID: |
MILK1_HUMAN |
| Immunogen Region: |
614-863 |
| Immunogen: |
Recombinant fusion protein containing a sequence corresponding to amino acids 614-863 of human MICALL1 (NP_203744.1). |
| Immunogen Sequence: |
VPSPGSSSPQLQVKSSCKEN PFNRKPSPAASPATKKATKG SKPVRPPAPGHGFPLIKRKV QADQYIPEEDIHGEMDTIER RLDALEHRGVLLEEKLRGGL NEGREDDMLVDWFKLIHEKH LLVRRESELIYVFKQQNLEQ RQADVEYELRCLLNKPEKDW TEEDRAREKVLMQELVTLIE QRNAIINCLDEDRQREEEED KMLEAMIKKKEFQREAEPEG KKKGKFKTMKMLKLLGNKR |
| Function | Probable lipid-binding protein with higher affinity for phosphatidic acid, a lipid enriched in recycling endosome membranes. On endosome membranes, may act as a downstream effector of Rab proteins recruiting cytosolic proteins to regulate membrane tubulation. May be involved in a late step of receptor-mediated endocytosis regulating for instance endocytosed-EGF receptor trafficking. Alternatively, may regulate slow endocytic recycling of endocytosed proteins back to the plasma membrane. May indirectly play a role in neurite outgrowth. |
| Protein Name | Mical-Like Protein 1Molecule Interacting With Rab13Mirab13 |
| Cellular Localisation | Recycling Endosome MembranePeripheral Membrane ProteinLate Endosome MembraneLocalization To Late Endosomes Is Actin-DependentAssociation To Tubular Recycling Endosomes Is Regulated By Rab35 And Arf6 |
| Alternative Antibody Names | Anti-Mical-Like Protein 1 antibodyAnti-Molecule Interacting With Rab13 antibodyAnti-Mirab13 antibodyAnti-MICALL1 antibodyAnti-KIAA1668 antibodyAnti-MIRAB13 antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
