| Host: |
Rabbit |
| Applications: |
WB/ELISA |
| Reactivity: |
Human |
| Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Clonality: |
Polyclonal |
| Conjugation: |
Unconjugated |
| Isotype: |
IgG |
| Formulation: |
PBS with 0.02% Sodium Azide, 50% Glycerol, pH 7.3. |
| Purification: |
Affinity purification |
| Concentration: |
Lot specific |
| Dilution Range: |
WB:1:1000-1:2000ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Gene Symbol: |
GRM2 |
| Gene ID: |
2912 |
| Uniprot ID: |
GRM2_HUMAN |
| Immunogen Region: |
410-540 aa |
| Specificity: |
Recombinant fusion protein containing a sequence corresponding to amino acids 410-540 of human mGluR2 (NP_000830.2). |
| Immunogen Sequence: |
MRPVNGRRLYKDFVLNVKFD APFRPADTHNEVRFDRFGDG IGRYNIFTYLRAGSGRYRYQ KVGYWAEGLTLDTSLIPWAS PSAGPLPASRCSEPCLQNEV KSVQPGEVCCWLCIPCQPYE YRLDEFTCADC |
| Tissue Specificity | Detected in brain cortex (at protein level). Widely expressed in different regions of the adult brain as well as in fetal brain. |
| Function | G-protein coupled receptor for glutamate. Ligand binding causes a conformation change that triggers signaling via guanine nucleotide-binding proteins (G proteins) and modulates the activity of down-stream effectors, such as adenylate cyclase. Signaling inhibits adenylate cyclase activity. May mediate suppression of neurotransmission or may be involved in synaptogenesis or synaptic stabilization. |
| Protein Name | Metabotropic Glutamate Receptor 2Mglur2 |
| Database Links | Reactome: R-HSA-418594Reactome: R-HSA-420499 |
| Cellular Localisation | Cell MembraneMulti-Pass Membrane ProteinSynapseCell ProjectionDendrite |
| Alternative Antibody Names | Anti-Metabotropic Glutamate Receptor 2 antibodyAnti-Mglur2 antibodyAnti-GRM2 antibodyAnti-GPRC1B antibodyAnti-MGLUR2 antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
