| Host: |
Rabbit |
| Applications: |
WB |
| Reactivity: |
Human/Mouse |
| Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description: |
Rabbit polyclonal antibody anti-MDH2 (59-338) is suitable for use in Western Blot research applications. |
| Clonality: |
Polyclonal |
| Conjugation: |
Unconjugated |
| Isotype: |
IgG |
| Formulation: |
PBS with 0.05% Proclin300, 50% Glycerol, pH7.3. |
| Purification: |
Affinity purification |
| Dilution Range: |
WB 1:500-1:2000 |
| Storage Instruction: |
Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: |
MDH2 |
| Gene ID: |
4191 |
| Uniprot ID: |
MDHM_HUMAN |
| Immunogen Region: |
59-338 |
| Immunogen: |
Recombinant fusion protein containing a sequence corresponding to amino acids 59-338 of human MDH2 (NP_005909.2). |
| Immunogen Sequence: |
AHTPGVAADLSHIETKAAVK GYLGPEQLPDCLKGCDVVVI PAGVPRKPGMTRDDLFNTNA TIVATLTAACAQHCPEAMIC VIANPVNSTIPITAEVFKKH GVYNPNKIFGVTTLDIVRAN TFVAELKGLDPARVNVPVIG GHAGKTIIPLISQCTPKVDF PQDQLTALTGRIQEAGTEVV KAKAGAGSATLSMAYAGARF VFSLVDAMNGKEGVVECSFV KSQETECTYFSTPLLLGKK |
| Post Translational Modifications | Acetylation is enhanced by up to 67% after treatment either with trichostin A (TSA) or with nicotinamide (NAM) with the appearance of tri- and tetraacetylations. Glucose also increases acetylation by about 60%. |
| Protein Name | Malate Dehydrogenase - Mitochondrial |
| Database Links | Reactome: R-HSA-70263Reactome: R-HSA-71403 |
| Cellular Localisation | Mitochondrion Matrix |
| Alternative Antibody Names | Anti-Malate Dehydrogenase - Mitochondrial antibodyAnti-MDH2 antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
