| Host: |
Rabbit |
| Applications: |
WB |
| Reactivity: |
Human/Mouse |
| Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description: |
Rabbit polyclonal antibody anti-MCPH1 (263-562) is suitable for use in Western Blot research applications. |
| Clonality: |
Polyclonal |
| Conjugation: |
Unconjugated |
| Isotype: |
IgG |
| Formulation: |
PBS with 0.02% Sodium Azide, 50% Glycerol, pH7.3. |
| Purification: |
Affinity purification |
| Dilution Range: |
WB 1:500-1:2000 |
| Storage Instruction: |
Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: |
MCPH1 |
| Gene ID: |
79648 |
| Uniprot ID: |
MCPH1_HUMAN |
| Immunogen Region: |
263-562 |
| Immunogen: |
Recombinant fusion protein containing a sequence corresponding to amino acids 263-562 of human MCPH1 (NP_001166046.1). |
| Immunogen Sequence: |
VTPDQKQAAGMSQETFEEKY RLSPTLSSTKGHLLIHSRPR SSSVKRKRVSHGSHSPPKEK CKRKRSTRRSIMPRLQLCRS EDRLQHVAGPALEALSCGES SYDDYFSPDNLKERYSENLP PESQLPSSPAQLSCRSLSKK ERTSIFEMSDFSCVGKKTRT VDITNFTAKTISSPRKTGNG EGRATSSCVTSAPEEALRCC RQAGKEDACPEGNGFSYTIE DPALPKGHDDDLTPLEGSL |
| Tissue Specificity | Expressed in fetal brain, liver and kidney. |
| Function | Implicated in chromosome condensation and DNA damage induced cellular responses. May play a role in neurogenesis and regulation of the size of the cerebral cortex. |
| Protein Name | Microcephalin |
| Database Links | Reactome: R-HSA-2299718 |
| Cellular Localisation | CytoplasmCytoskeletonMicrotubule Organizing CenterCentrosome |
| Alternative Antibody Names | Anti-Microcephalin antibodyAnti-MCPH1 antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
