• Western blot analysis of lysates from A549 cells, using MAGI2 Antibody. The lane on the right is blocked with the synthesized peptide.
  • Western blot analysis of the lysates from 293 cells using MAGI2 antibody.
  • Immunohistochemical analysis of paraffin-embedded Human breast cancer. Antibody was diluted at 1:100 (4°C overnight). High-pressure and temperature Tris-EDTA, pH8.0 was used for antigen retrieval. Negetive contrl (right) obtaned from antibody was pre-absorbed by immunogen peptide.

Anti-MAGI2 antibody (221-270 aa) (STJ93992)

SKU:
STJ93992

£46.00 - £226.00
Current Stock:
Host: Rabbit
Applications: WB/IHC/IF/ELISA
Reactivity: Human/Mouse/Rat
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description: Rabbit polyclonal antibody anti-Membrane-associated guanylate kinase, WW and PDZ domain-containing protein 2 (221-270 aa) is suitable for use in Western Blot, Immunohistochemistry, Immunofluorescence and ELISA research applications.
Clonality: Polyclonal
Conjugation: Unconjugated
Isotype: IgG
Formulation: Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide.
Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Concentration: 1 mg/mL
Dilution Range: WB 1:500-1:2000
IHC 1:100-1:300
ELISA 1:20000
IF 1:50-200
Storage Instruction: Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.
Gene Symbol: MAGI2
Gene ID: 9863
Uniprot ID: MAGI2_HUMAN
Immunogen Region: 221-270 aa
Specificity: MAGI-2 Polyclonal Antibody detects endogenous levels of MAGI-2 protein.
Immunogen: The antiserum was produced against synthesized peptide derived from the human MAGI2 at the amino acid range 221-270
Function Seems to act as a scaffold molecule at synaptic junctions by assembling neurotransmitter receptors and cell adhesion proteins. Plays a role in nerve growth factor (NGF)-induced recruitment of RAPGEF2 to late endosomes and neurite outgrowth. May play a role in regulating activin-mediated signaling in neuronal cells. Enhances the ability of PTEN to suppress AKT1 activation. Plays a role in receptor-mediated clathrin-dependent endocytosis which is required for ciliogenesis.
Protein Name Membrane-Associated Guanylate Kinase - Ww And Pdz Domain-Containing Protein 2
Atrophin-1-Interacting Protein 1
Aip-1
Atrophin-1-Interacting Protein A
Membrane-Associated Guanylate Kinase Inverted 2
Magi-2
Database Links Reactome: R-HSA-373753
Cellular Localisation Cytoplasm
Late Endosome
Synapse
Synaptosome
Cell Membrane
Peripheral Membrane Protein
Cytoskeleton
Microtubule Organizing Center
Centrosome
Cell Projection
Cilium
Centriole
Photoreceptor Inner Segment
Photoreceptor Outer Segment
Localized Diffusely In The Cytoplasm Before Nerve Growth Factor (Ngf) Stimulation
Recruited To Late Endosomes After Ngf Stimulation
Membrane-Associated In Synaptosomes
Alternative Antibody Names Anti-Membrane-Associated Guanylate Kinase - Ww And Pdz Domain-Containing Protein 2 antibody
Anti-Atrophin-1-Interacting Protein 1 antibody
Anti-Aip-1 antibody
Anti-Atrophin-1-Interacting Protein A antibody
Anti-Membrane-Associated Guanylate Kinase Inverted 2 antibody
Anti-Magi-2 antibody
Anti-MAGI2 antibody
Anti-ACVRINP1 antibody
Anti-AIP1 antibody
Anti-KIAA0705 antibody

Information sourced from Uniprot.org

12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance