• Western blot analysis of extracts of various cell lines, using LTB4R antibody (STJ11102751) at 1:1000 dilution. Secondary antibody: HRP Goat Anti-rabbit IgG (H+L) at 1:10000 dilution. Lysates/proteins: 25ug per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit. Exposure time: 10s.
  • Western blot analysis of extracts of various cell lines, using LTB4R antibody (STJ11102751) at 1:1000 dilution. Secondary antibody: HRP Goat Anti-rabbit IgG (H+L) at 1:10000 dilution. Lysates/proteins: 25ug per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit. Exposure time: 180s.

Anti-LTB4R antibody (253-352) [S1MR] (STJ11102751)

SKU:
STJ11102751

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Host: Rabbit
Applications: WB
Reactivity: Mouse/Rat
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description: Rabbit monoclonal antibody anti-LTB4R (253-352) is suitable for use in Western Blot research applications.
Clonality: Monoclonal
Clone ID: S1MR
Conjugation: Unconjugated
Isotype: IgG
Formulation: PBS with 0.02% Sodium Azide, 0.05% BSA, 50% Glycerol, pH7.3.
Purification: Affinity purification
Dilution Range: WB 1:500-1:1000
Storage Instruction: Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.
Gene Symbol: LTB4R
Gene ID: 1241
Uniprot ID: LT4R1_HUMAN
Immunogen Region: 253-352
Immunogen: A synthetic peptide corresponding to a sequence within amino acids 253-352 of human LTB4R (Q15722).
Immunogen Sequence: AAGLGLVGKRLSLARNVLIA LAFLSSSVNPVLYACAGGGL LRSAGVGFVAKLLEGTGSEA SSTRRGGSLGQTARSGPAAL EPGPSESLTASSPLKLNELN
Tissue Specificity Expressed at highest levels in heart, skeletal muscle and at lower levels in brain and liver. High level of expression in lymphoid tissues.
Post Translational Modifications Phosphorylated by GRK6 upon leukotriene B4 binding.which promotes desensitization.
Function Receptor for extracellular ATP > UTP and ADP. The activity of this receptor is mediated by G proteins which activate a phosphatidylinositol-calcium second messenger system. May be the cardiac P2Y receptor involved in the regulation of cardiac muscle contraction through modulation of L-type calcium currents. Is a receptor for leukotriene B4, a potent chemoattractant involved in inflammation and immune response.
Protein Name Leukotriene B4 Receptor 1
Ltb4-R 1
Ltb4-R1
Chemoattractant Receptor-Like 1
G-Protein Coupled Receptor 16
P2y Purinoceptor 7
P2y7
Database Links Reactome: R-HSA-391906
Reactome: R-HSA-416476
Cellular Localisation Cell Membrane
Multi-Pass Membrane Protein
Alternative Antibody Names Anti-Leukotriene B4 Receptor 1 antibody
Anti-Ltb4-R 1 antibody
Anti-Ltb4-R1 antibody
Anti-Chemoattractant Receptor-Like 1 antibody
Anti-G-Protein Coupled Receptor 16 antibody
Anti-P2y Purinoceptor 7 antibody
Anti-P2y7 antibody
Anti-LTB4R antibody
Anti-BLT antibody
Anti-BLT1 antibody
Anti-BLTR antibody
Anti-CMKRL1 antibody
Anti-GPR16 antibody
Anti-P2RY7 antibody

Information sourced from Uniprot.org

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