| Host: |
Mouse |
| Applications: |
WB |
| Reactivity: |
Human |
| Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description: |
Mouse monoclonal antibody anti-Leucine-rich repeat flightless-interacting protein 1 is suitable for use in Western Blot research applications. |
| Clonality: |
Monoclonal |
| Conjugation: |
Unconjugated |
| Formulation: |
Liquid in 0.1M Tris-Glycine (pH7.4, 150 mM NaCl) , 0.2% Sodium Azide and 50% Glycerol. |
| Purification: |
Affinity purification |
| Concentration: |
1 mg/mL |
| Dilution Range: |
WB 1:1000-1:2000 |
| Storage Instruction: |
Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: |
LRRFIP1 |
| Gene ID: |
9208 |
| Uniprot ID: |
LRRF1_HUMAN |
| Specificity: |
LRRFIP1 Monoclonal Antibody detects endogenous levels of LRRFIP1 protein. |
| Immunogen: |
Purified recombinant human LRRFIP1 protein fragments expressed in E.coli. |
| Function | Transcriptional repressor which preferentially binds to the GC-rich consensus sequence (5'-AGCCCCCGGCG-3') and may regulate expression of TNF, EGFR and PDGFA. May control smooth muscle cells proliferation following artery injury through PDGFA repression. May also bind double-stranded RNA. Positively regulates Toll-like receptor (TLR) signaling in response to agonist probably by competing with the negative FLII regulator for MYD88-binding. |
| Protein Name | Leucine-Rich Repeat Flightless-Interacting Protein 1Lrr Flii-Interacting Protein 1Gc-Binding Factor 2Tar Rna-Interacting Protein |
| Database Links | Reactome: R-HSA-1839117Reactome: R-HSA-3134973Reactome: R-HSA-5655302 |
| Cellular Localisation | NucleusCytoplasm |
| Alternative Antibody Names | Anti-Leucine-Rich Repeat Flightless-Interacting Protein 1 antibodyAnti-Lrr Flii-Interacting Protein 1 antibodyAnti-Gc-Binding Factor 2 antibodyAnti-Tar Rna-Interacting Protein antibodyAnti-LRRFIP1 antibodyAnti-GCF2 antibodyAnti-TRIP antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
