| Host: |
Rabbit |
| Applications: |
WB/IHC/IP |
| Reactivity: |
Human/Mouse/Rat |
| Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description: |
Rabbit polyclonal antibody anti-LRRC59 (1-244) is suitable for use in Western Blot, Immunohistochemistry and Immunoprecipitation research applications. |
| Clonality: |
Polyclonal |
| Conjugation: |
Unconjugated |
| Isotype: |
IgG |
| Formulation: |
PBS with 0.02% Sodium Azide, 50% Glycerol, pH7.3. |
| Purification: |
Affinity purification |
| Dilution Range: |
WB 1:500-1:2000IHC-P 1:50-1:200IP 1:50-1:100 |
| Storage Instruction: |
Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: |
LRRC59 |
| Gene ID: |
55379 |
| Uniprot ID: |
LRC59_HUMAN |
| Immunogen Region: |
1-244 |
| Immunogen: |
Recombinant fusion protein containing a sequence corresponding to amino acids 1-244 of human LRRC59 (NP_060979.2). |
| Immunogen Sequence: |
MTKAGSKGGNLRDKLDGNEL DLSLSDLNEVPVKELAALPK ATILDLSCNKLTTLPSDFCG LTHLVKLDLSKNKLQQLPAD FGRLVNLQHLDLLNNKLVTL PVSFAQLKNLKWLDLKDNPL DPVLAKVAGDCLDEKQCKQC ANKVLQHMKAVQADQERERQ RRLEVEREAEKKREAKQRAK EAQERELRKREKAEEKERRR KEYDALKAAKREQEKKPKKE ANQAPKSKSGSRPRKPPPR |
| Tissue Specificity | Widely expressed. |
| Function | Required for nuclear import of FGF1, but not that of FGF2. Might regulate nuclear import of exogenous FGF1 by facilitating interaction with the nuclear import machinery and by transporting cytosolic FGF1 to, and possibly through, the nuclear pores. |
| Protein Name | Leucine-Rich Repeat-Containing Protein 59Ribosome-Binding Protein P34P34 Cleaved Into - Leucine-Rich Repeat-Containing Protein 59 - N-Terminally Processed |
| Cellular Localisation | Microsome MembraneSingle-Pass Type Ii Membrane ProteinEndoplasmic Reticulum MembraneNucleus EnvelopeLocalization In The Nuclear Envelope Depends Upon The Nuclear Import MachineryIncluding Kpnb1 |
| Alternative Antibody Names | Anti-Leucine-Rich Repeat-Containing Protein 59 antibodyAnti-Ribosome-Binding Protein P34 antibodyAnti-P34 Cleaved Into - Leucine-Rich Repeat-Containing Protein 59 - N-Terminally Processed antibodyAnti-LRRC59 antibodyAnti-PRO1855 antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
![Western blot analysis of lysates from wild type (WT) and LRRC59 knockout (KO) 293T cells, using [KO Validated] LRRC59 Rabbit polyclonal antibody (STJ11100841) at 1:1000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (STJS000856) at 1:10000 dilution. Lysates/proteins: 25 Mu g per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit. Exposure time: 5s.](https://cdn11.bigcommerce.com/s-zso2xnchw9/images/stencil/300x300/products/89775/358247/STJ11100841_1__11256.1713122582.jpg?c=1 "Western blot analysis of lysates from wild type (WT) and LRRC59 knockout (KO) 293T cells, using [KO Validated] LRRC59 Rabbit polyclonal antibody (STJ11100841) at 1:1000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (STJS000856) at 1:10000 dilution. Lysates/proteins: 25 Mu g per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit. Exposure time: 5s.")
