• Western blot analysis of extracts of various cell lines, using LRIG1 antibody (STJ113928) at 1:3000 dilution. Secondary antibody: HRP Goat Anti-rabbit IgG (H+L) at 1:10000 dilution. Lysates/proteins: 25ug per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit. Exposure time: 90s.

Anti-LRIG1 antibody (816-1093) (STJ113928)

SKU:
STJ113928

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Host: Rabbit
Applications: WB
Reactivity: Human
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description: Rabbit polyclonal antibody anti-LRIG1 (816-1093) is suitable for use in Western Blot research applications.
Clonality: Polyclonal
Conjugation: Unconjugated
Isotype: IgG
Formulation: PBS with 0.01% Thimerosal, 50% Glycerol, pH7.3.
Purification: Affinity purification
Dilution Range: WB 1:500-1:2000
Storage Instruction: Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.
Gene Symbol: LRIG1
Gene ID: 26018
Uniprot ID: LRIG1_HUMAN
Immunogen Region: 816-1093
Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 816-1093 of human LRIG1 (NP_056356.2).
Immunogen Sequence: YQTRKKSEEYSVTNTDETVV PPDVPSYLSSQGTLSDRQET VVRTEGGPQANGHIESNGVC PRDASHFPEPDTHSVACRQP KLCAGSAYHKEPWKAMEKAE GTPGPHKMEHGGRVVCSDCN TEVDCYSRGQAFHPQPVSRD SAQPSAPNGPEPGGSDQEHS PHHQCSRTAAGSCPECQGSL YPSNHDRMLTAVKKKPMASL DGKGDSSWTLARLYHPDSTE LQPASSLTSGSPERAEAQY
Tissue Specificity Widely expressed.
Function Acts as a feedback negative regulator of signaling by receptor tyrosine kinases, through a mechanism that involves enhancement of receptor ubiquitination and accelerated intracellular degradation.
Protein Name Leucine-Rich Repeats And Immunoglobulin-Like Domains Protein 1
Lig-1
Database Links Reactome: R-HSA-177929
Reactome: R-HSA-6807004
Cellular Localisation Cell Membrane
Single-Pass Type I Membrane Protein
Alternative Antibody Names Anti-Leucine-Rich Repeats And Immunoglobulin-Like Domains Protein 1 antibody
Anti-Lig-1 antibody
Anti-LRIG1 antibody
Anti-LIG1 antibody

Information sourced from Uniprot.org

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