| Host: | Rabbit |
| Applications: | WB/ELISA |
| Reactivity: | Human/Rat |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Clonality : | Polyclonal |
| Conjugation: | Unconjugated |
| Isotype: | IgG |
| Formulation: | PBS with 0.02% Sodium Azide, 50% Glycerol, pH 7.3. |
| Purification: | Affinity purification |
| Concentration: | Lot specific |
| Dilution Range: | WB:1:200-1:2000ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: | KIFC3 |
| Gene ID: | 3801 |
| Uniprot ID: | KIFC3_HUMAN |
| Immunogen Region: | 140-390 |
| Specificity: | Recombinant fusion protein containing a sequence corresponding to amino acids 140-390 of human KIFC3 (NP_005541.3). |
| Immunogen Sequence: | MVENERLRQEMRRCEAELQE LRTKPAGPCPGCEHSQESAQ LRDKLSQLQLEMAESKGMLS ELNLEVQQKTDRLAEVELRL KDCLAEKAQEEERLSRRLRD SHETIASLRAQSPPVKYVIK TVEVESSKTKQALSESQARN QHLQEQVAMQRQVLKEMEQQ LQSSHQLTARLRAQIAMYES ELERAHGQMLEEMQSLEEDK NRAIEEAFARAQVEMKAVHE NLAGVRTNLLTLQPALRTL |
| Function | Minus-end microtubule-dependent motor protein. Involved in apically targeted transport. Required for zonula adherens maintenance. |
| Protein Name | Kinesin-Like Protein Kifc3 |
| Database Links | Reactome: R-HSA-390471 Q9BVG8-2 |
| Cellular Localisation | Cell JunctionAdherens JunctionCytoplasmCytoskeletonMicrotubule Organizing CenterCentrosomeCytoplasmic Vesicle MembranePeripheral Membrane ProteinApical Cell MembraneOn Membrane Organelles Immediately Beneath The Apical Plasma Membrane Of Renal Tubular Epithelial CellsLocalized In The Distal Tubules And Loops Of Henle In The KidneyBut Not In The Proximal Tubules Or The GlomeruliWith Stronger Staining In The Apical Area Of These Epithelial CellsLocalizes Along Zonula Adherens Only At Mature Cell-Cell Contacts |
| Alternative Antibody Names | Anti-Kinesin-Like Protein Kifc3 antibodyAnti-KIFC3 antibody |
Information sourced from Uniprot.org