Host: | Mouse |
Applications: | IHC-P |
Reactivity: | Human |
Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Short Description : | Mouse monoclonal antibody anti-Inhibin A is suitable for use in Immunohistochemistry research applications. |
Clonality : | Monoclonal |
Clone ID : | AMY82 |
Conjugation: | Unconjugated |
Isotype: | IgG1 |
Formulation: | Tissue culture supernatant with 15mM Sodium azide |
Concentration: | >=214 mg/L |
Dilution Range: | IHC-P 1:100 |
Storage Instruction: | Store at 2-8°C upon receipt. |
Immunogen: | Prokaryotic recombinant protein corresponding to 134 amino acids of the human inhibin alpha molecule. |
Background | Inhibins and activins are members of the transforming growth factor beta (TGF Beta ) family of cytokines. Inhibins are heterodimers consisting of a common Alpha-subunit linked to either a Beta A subunit ( Alpha-Beta A, forming inhibin A) or a Beta B subunit ( Alpha-Beta B, forming inhibin B). Activins share the Beta-subunit with the inhibins and may be homo or heterodimers of Beta-subunits forming activin A ( Beta A-Beta A) , activin AB ( Beta A-Beta B) or activin B ( Beta B-Beta B). The expression of the Alpha-subunit, and therefore of inhibins appears to be more restricted than that of the Beta-subunit, and therefore of activins. Inhibins and activins play a role in the regulation of pituitary follicle stimulating hormone (FSH) secretion. |
Information sourced from Uniprot.org