| Host: |
Rabbit |
| Applications: |
WB |
| Reactivity: |
Human/Mouse/Rat |
| Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description: |
Rabbit polyclonal antibody anti-HSH2D (15-115) is suitable for use in Western Blot research applications. |
| Clonality: |
Polyclonal |
| Conjugation: |
Unconjugated |
| Isotype: |
IgG |
| Formulation: |
PBS with 0.01% Thimerosal, 50% Glycerol, pH7.3. |
| Purification: |
Affinity purification |
| Dilution Range: |
WB 1:500-1:2000 |
| Storage Instruction: |
Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: |
HSH2D |
| Gene ID: |
84941 |
| Uniprot ID: |
HSH2D_HUMAN |
| Immunogen Region: |
15-115 |
| Immunogen: |
Recombinant fusion protein containing a sequence corresponding to amino acids 15-115 of human HSH2D (NP_001278203.1). |
| Immunogen Sequence: |
RAQSSCCHFMVKLLDDGTFM IPGEKVAHTSLDALVTFHQQ KPIEPRRELLTQPCRQKDPA NVDYEDLFLYSNAVAEEAAC PVSAPEEASPKPVLCHQSKE R |
| Tissue Specificity | Predominantly expressed in spleen and hematopoietic cells such as peripheral blood leukocytes and weakly expressed in prostate, thymus, heart, small intestine and placenta. |
| Post Translational Modifications | May be phosphorylated by FES and ACK1. |
| Function | May be a modulator of the apoptotic response through its ability to affect mitochondrial stability. Adapter protein involved in tyrosine kinase and CD28 signaling. Seems to affect CD28-mediated activation of the RE/AP element of the interleukin-2 promoter. |
| Protein Name | Hematopoietic Sh2 Domain-Containing ProteinHematopoietic Sh2 ProteinAdaptor In Lymphocytes Of Unknown Function X |
| Cellular Localisation | CytoplasmNucleus |
| Alternative Antibody Names | Anti-Hematopoietic Sh2 Domain-Containing Protein antibodyAnti-Hematopoietic Sh2 Protein antibodyAnti-Adaptor In Lymphocytes Of Unknown Function X antibodyAnti-HSH2D antibodyAnti-ALX antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
