| Host: |
Rabbit |
| Applications: |
WB |
| Reactivity: |
Human/Mouse/Rat |
| Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description: |
Rabbit polyclonal antibody anti-HNF1B (1-190) is suitable for use in Western Blot research applications. |
| Clonality: |
Polyclonal |
| Conjugation: |
Unconjugated |
| Isotype: |
IgG |
| Formulation: |
PBS with 0.01% Thimerosal, 50% Glycerol, pH7.3. |
| Purification: |
Affinity purification |
| Dilution Range: |
WB 1:500-1:1000 |
| Storage Instruction: |
Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: |
HNF1B |
| Gene ID: |
6928 |
| Uniprot ID: |
HNF1B_HUMAN |
| Immunogen Region: |
1-190 |
| Immunogen: |
Recombinant fusion protein containing a sequence corresponding to amino acids 1-190 of HNF1B (NP_000449.1). |
| Immunogen Sequence: |
MVSKLTSLQQELLSALLSSG VTKEVLVQALEELLPSPNFG VKLETLPLSPGSGAEPDTKP VFHTLTNGHAKGRLSGDEGS EDGDDYDTPPILKELQALNT EEAAEQRAEVDRMLSEDPWR AAKMIKGYMQQHNIPQREVV DVTGLNQSHLSQHLNKGTPM KTQKRAALYTWYVRKQREIL RQFNQTVQSS |
| Function | Transcription factor that binds to the inverted palindrome 5'-GTTAATNATTAAC-3'. Binds to the FPC element in the cAMP regulatory unit of the PLAU gene. Transcriptional activity is increased by coactivator PCBD1. |
| Protein Name | Hepatocyte Nuclear Factor 1-BetaHnf-1-BetaHnf-1bHomeoprotein Lfb3Transcription Factor 2Tcf-2Variant Hepatic Nuclear Factor 1Vhnf1 |
| Database Links | Reactome: R-HSA-210744Reactome: R-HSA-210747 |
| Cellular Localisation | Nucleus |
| Alternative Antibody Names | Anti-Hepatocyte Nuclear Factor 1-Beta antibodyAnti-Hnf-1-Beta antibodyAnti-Hnf-1b antibodyAnti-Homeoprotein Lfb3 antibodyAnti-Transcription Factor 2 antibodyAnti-Tcf-2 antibodyAnti-Variant Hepatic Nuclear Factor 1 antibodyAnti-Vhnf1 antibodyAnti-HNF1B antibodyAnti-TCF2 antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
![Western blot analysis of lysates from wild type (WT) and MYOF knockout (KO) HeLa (KO) cells, using [KO Validated] MYOF Rabbit polyclonal antibody (STJ117622) at 1:1000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (STJS000856) at 1:10000 dilution. Lysates/proteins: 25 Mu g per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit. Exposure time: 1s.](https://cdn11.bigcommerce.com/s-zso2xnchw9/images/stencil/300x300/products/96581/379140/STJ117622_1__97810.1713146869.jpg?c=1 "Western blot analysis of lysates from wild type (WT) and MYOF knockout (KO) HeLa (KO) cells, using [KO Validated] MYOF Rabbit polyclonal antibody (STJ117622) at 1:1000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (STJS000856) at 1:10000 dilution. Lysates/proteins: 25 Mu g per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit. Exposure time: 1s.")