| Host: |
Rabbit |
| Applications: |
WB/IF/ICC/ELISA |
| Reactivity: |
Human/Mouse/Rat |
| Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Clonality: |
Polyclonal |
| Conjugation: |
Unconjugated |
| Isotype: |
IgG |
| Formulation: |
PBS with 0.02% Sodium Azide, 50% Glycerol, pH 7.3. |
| Purification: |
Affinity purification |
| Concentration: |
Lot specific |
| Dilution Range: |
WB:1:100-1:500IF/ICC:1:50-1:100ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Storage Instruction: |
Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: |
HMG20A |
| Gene ID: |
10363 |
| Uniprot ID: |
HM20A_HUMAN |
| Immunogen Region: |
1-347 |
| Specificity: |
Recombinant fusion protein containing a sequence corresponding to amino acids 1-347 of human HMG20A (NP_060670.1). |
| Immunogen Sequence: |
MENLMTSSTLPPLFADEDGS KESNDLATTGLNHPEVPYSS GATSSTNNPEFVEDLSQGQL LQSESSNAAEGNEQRHEDEQ RSKRGGWSKGRKRKKPLRDS NAPKSPLTGYVRFMNERREQ LRAKRPEVPFPEITRMLGNE WSKLPPEEKQRYLDEADRDK ERYMKELEQYQKTEAYKVFS RKTQDRQKGKSHRQDAARQA THDHEKETEVKERSVFDIPI FTEEFLNHSKAREAELRQL |
| Tissue Specificity | Ubiquitous. |
| Function | Plays a role in neuronal differentiation as chromatin-associated protein. Acts as inhibitor of HMG20B. Overcomes the repressive effects of the neuronal silencer REST and induces the activation of neuronal-specific genes. Involved in the recruitment of the histone methyltransferase KMT2A/MLL1 and consequent increased methylation of histone H3 lysine 4. |
| Protein Name | High Mobility Group Protein 20aHmg Box-Containing Protein 20aHmg Domain-Containing Protein 1Hmg Domain-Containing Protein Hmgx1 |
| Cellular Localisation | Nucleus |
| Alternative Antibody Names | Anti-High Mobility Group Protein 20a antibodyAnti-Hmg Box-Containing Protein 20a antibodyAnti-Hmg Domain-Containing Protein 1 antibodyAnti-Hmg Domain-Containing Protein Hmgx1 antibodyAnti-HMG20A antibodyAnti-HMGX1 antibodyAnti-HMGXB1 antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
