| Host: | Rabbit |
| Applications: | WB/IF/ICC/ELISA |
| Reactivity: | Human/Mouse/Rat |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Clonality : | Polyclonal |
| Conjugation: | Unconjugated |
| Isotype: | IgG |
| Formulation: | PBS with 0.02% Sodium Azide, 50% Glycerol, pH 7.3. |
| Purification: | Affinity purification |
| Concentration: | Lot specific |
| Dilution Range: | WB:1:500-1:2000IF/ICC:1:10-1:100ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: | HAGH |
| Gene ID: | 3029 |
| Uniprot ID: | GLO2_HUMAN |
| Immunogen Region: | 1-260 |
| Specificity: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-260 of human HAGH (NP_001035517.1). |
| Immunogen Sequence: | MKVEVLPALTDNYMYLVIDD ETKEAAIVDPVQPQKVVDAA RKHGVKLTTVLTTHHHWDHA GGNEKLVKLESGLKVYGGDD RIGALTHKITHLSTLQVGSL NVKCLATPCHTSGHICYFVS KPGGSEPPAVFTGDTLFVAG CGKFYEGTADEMCKALLEVL GRLPPDTRVYCGHEYTINNL KFARHVEPGNAAIREKLAWA KEKYSIGEPTVPSTLAEEFT YNPFMRVREKTVQQHAGET |
| Tissue Specificity | Expressed in liver and kidney. |
| Function | Thiolesterase that catalyzes the hydrolysis of S-D-lactoyl-glutathione to form glutathione and D-lactic acid. |
| Protein Name | Hydroxyacylglutathione Hydrolase - MitochondrialGlyoxalase IiGlx Ii |
| Database Links | Reactome: R-HSA-70268 Q16775-2 |
| Cellular Localisation | Isoform 1: Mitochondrion MatrixIsoform 2: Cytoplasm |
| Alternative Antibody Names | Anti-Hydroxyacylglutathione Hydrolase - Mitochondrial antibodyAnti-Glyoxalase Ii antibodyAnti-Glx Ii antibodyAnti-HAGH antibodyAnti-GLO2 antibodyAnti-HAGH1 antibody |
Information sourced from Uniprot.org
