Anti-GPR119 antibody (200-300) (STJ11100495)

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STJ11100495

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Host: Rabbit
Applications: WB
Reactivity: Human
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description: Rabbit polyclonal antibody anti-GPR119 (200-300) is suitable for use in Western Blot research applications.
Clonality: Polyclonal
Conjugation: Unconjugated
Isotype: IgG
Formulation: PBS with 0.01% Thimerosal, 50% Glycerol, pH7.3.
Purification: Affinity purification
Dilution Range: WB 1:500-1:2000
Storage Instruction: Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.
Gene Symbol: GPR119
Gene ID: 139760
Uniprot ID: GP119_HUMAN
Immunogen Region: 200-300
Immunogen: A synthetic peptide corresponding to a sequence within amino acids 200-300 of human GPR119 (NP_848566.1).
Immunogen Sequence: RKMEHAGAMAGGYRSPRTPS DFKALRTVSVLIGSFALSWT PFLITGIVQVACQECHLYLV LERYLWLLGVGNSLLNPLIY AYWQKEVRLQLYHMALGVKK V
Tissue Specificity Predominantly expressed in the pancreas, especially in the islets.
Function Receptor for the endogenous fatty-acid ethanolamide oleoylethanolamide (OEA) and lysophosphatidylcholine (LPC). Functions as a glucose-dependent insulinotropic receptor. The activity of this receptor is mediated by G proteins which activate adenylate cyclase. Seems to act through a G(s) mediated pathway.
Protein Name Glucose-Dependent Insulinotropic Receptor
G-Protein Coupled Receptor 119
Database Links Reactome: R-HSA-381771
Reactome: R-HSA-400511
Cellular Localisation Cell Membrane
Multi-Pass Membrane Protein
Alternative Antibody Names Anti-Glucose-Dependent Insulinotropic Receptor antibody
Anti-G-Protein Coupled Receptor 119 antibody
Anti-GPR119 antibody

Information sourced from Uniprot.org

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