| Host: |
Rabbit |
| Applications: |
WB |
| Reactivity: |
Human |
| Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description: |
Rabbit polyclonal antibody anti-GPR119 (200-300) is suitable for use in Western Blot research applications. |
| Clonality: |
Polyclonal |
| Conjugation: |
Unconjugated |
| Isotype: |
IgG |
| Formulation: |
PBS with 0.01% Thimerosal, 50% Glycerol, pH7.3. |
| Purification: |
Affinity purification |
| Dilution Range: |
WB 1:500-1:2000 |
| Storage Instruction: |
Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: |
GPR119 |
| Gene ID: |
139760 |
| Uniprot ID: |
GP119_HUMAN |
| Immunogen Region: |
200-300 |
| Immunogen: |
A synthetic peptide corresponding to a sequence within amino acids 200-300 of human GPR119 (NP_848566.1). |
| Immunogen Sequence: |
RKMEHAGAMAGGYRSPRTPS DFKALRTVSVLIGSFALSWT PFLITGIVQVACQECHLYLV LERYLWLLGVGNSLLNPLIY AYWQKEVRLQLYHMALGVKK V |
| Tissue Specificity | Predominantly expressed in the pancreas, especially in the islets. |
| Function | Receptor for the endogenous fatty-acid ethanolamide oleoylethanolamide (OEA) and lysophosphatidylcholine (LPC). Functions as a glucose-dependent insulinotropic receptor. The activity of this receptor is mediated by G proteins which activate adenylate cyclase. Seems to act through a G(s) mediated pathway. |
| Protein Name | Glucose-Dependent Insulinotropic ReceptorG-Protein Coupled Receptor 119 |
| Database Links | Reactome: R-HSA-381771Reactome: R-HSA-400511 |
| Cellular Localisation | Cell MembraneMulti-Pass Membrane Protein |
| Alternative Antibody Names | Anti-Glucose-Dependent Insulinotropic Receptor antibodyAnti-G-Protein Coupled Receptor 119 antibodyAnti-GPR119 antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
