• Western blot analysis of extracts of various cell lines, using GNAL antibody (STJ114670) at 1:3000 dilution. Secondary antibody: HRP Goat Anti-rabbit IgG (H+L) at 1:10000 dilution. Lysates/proteins: 25ug per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit. Exposure time: 10s.

Anti-GNAL antibody (1-120) (STJ114670)

SKU:
STJ114670

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Host: Rabbit
Applications: WB
Reactivity: Human/Mouse
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description: Rabbit polyclonal antibody anti-GNAL (1-120) is suitable for use in Western Blot research applications.
Clonality: Polyclonal
Conjugation: Unconjugated
Isotype: IgG
Formulation: PBS with 0.01% Thimerosal, 50% Glycerol, pH7.3.
Purification: Affinity purification
Dilution Range: WB 1:1000-1:2000
Storage Instruction: Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.
Gene Symbol: GNAL
Gene ID: 2774
Uniprot ID: GNAL_HUMAN
Immunogen Region: 1-120
Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 1-120 of human GNAL (NP_892023.1).
Immunogen Sequence: MGLCYSLRPLLFGGPGDDPC AASEPPVEDAQPAPAPALAP VRAAARDTARTLLPRGGEGS PACARPKADKPKEKRQRTEQ LSAEEREAAKEREAVKEARK VSRGIDRMLRDQKRDLQQTH
Tissue Specificity Detected in olfactory neuroepithelium, brain, testis, and to a lower extent in retina, lung alveoli, spleen. Trace amounts where seen in kidney, adrenal gland and liver. Found to be expressed in all the insulinomas examined.
Function Guanine nucleotide-binding proteins (G proteins) are involved as modulators or transducers in various transmembrane signaling systems. G(olf) alpha mediates signal transduction within the olfactory neuroepithelium and the basal ganglia. May be involved in some aspect of visual transduction, and in mediating the effect of one or more hormones/neurotransmitters.
Protein Name Guanine Nucleotide-Binding Protein G(Olf Subunit Alpha
Adenylate Cyclase-Stimulating G Alpha Protein - Olfactory Type
Database Links Reactome: R-HSA-170660
Reactome: R-HSA-170670
Reactome: R-HSA-381753
Alternative Antibody Names Anti-Guanine Nucleotide-Binding Protein G(Olf Subunit Alpha antibody
Anti-Adenylate Cyclase-Stimulating G Alpha Protein - Olfactory Type antibody
Anti-GNAL antibody

Information sourced from Uniprot.org

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