| Host: |
Rabbit |
| Applications: |
WB |
| Reactivity: |
Mouse/Rat |
| Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description: |
Rabbit polyclonal antibody anti-GLE1 (1-300) is suitable for use in Western Blot research applications. |
| Clonality: |
Polyclonal |
| Conjugation: |
Unconjugated |
| Isotype: |
IgG |
| Formulation: |
PBS with 0.01% Thimerosal, 50% Glycerol, pH7.3. |
| Purification: |
Affinity purification |
| Dilution Range: |
WB 1:1000-1:2000 |
| Storage Instruction: |
Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: |
GLE1 |
| Gene ID: |
2733 |
| Uniprot ID: |
GLE1_HUMAN |
| Immunogen Region: |
1-300 |
| Immunogen: |
Recombinant fusion protein containing a sequence corresponding to amino acids 1-300 of human GLE1 (NP_001003722.1). |
| Immunogen Sequence: |
MPSEGRCWETLKALRSSDKG RLCYYRDWLLRREDVLEECM SLPKLSSYSGWVVEHVLPHM QENQPLSETSPSSTSASALD QPSFVPKSPDASSAFSPASP ATPNGTKGKDESQHTESMVL QSSRGIKVEGCVRMYELVHR MKGTEGLRLWQEEQERKVQA LSEMASEQLKRFDEWKELKQ HKEFQDLREVMEKSSREALG HQEKLKAEHRHRAKILNLKL REAEQQRVKQAEQERLRKE |
| Function | Required for the export of mRNAs containing poly(A) tails from the nucleus into the cytoplasm. May be involved in the terminal step of the mRNA transport through the nuclear pore complex (NPC). |
| Protein Name | Mrna Export Factor Gle1Hgle1Gle1 Rna Export MediatorGle1-Like ProteinNucleoporin Gle1 |
| Database Links | Reactome: R-HSA-159236 |
| Cellular Localisation | NucleusCytoplasmShuttles Between The Nucleus And The CytoplasmShuttling Is Essential For Its Mrna Export FunctionIsoform 1: CytoplasmNuclear Pore ComplexIn The NucleusIsoform 1 Localizes To The Nuclear Pore Complex And Nuclear Envelope |
| Alternative Antibody Names | Anti-Mrna Export Factor Gle1 antibodyAnti-Hgle1 antibodyAnti-Gle1 Rna Export Mediator antibodyAnti-Gle1-Like Protein antibodyAnti-Nucleoporin Gle1 antibodyAnti-GLE1 antibodyAnti-GLE1L antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
![Western blot analysis of lysates from wild type (WT) and BUB1 knockout (KO) HeLa cells, using [KO Validated] BUB1 Rabbit polyclonal antibody (STJ11100026) at 1:1000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (STJS000856) at 1:10000 dilution. Lysates/proteins: 25 Mu g per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit. Exposure time: 1min.](https://cdn11.bigcommerce.com/s-zso2xnchw9/images/stencil/300x300/products/89098/357557/STJ11100026_1__69013.1713121681.jpg?c=1 "Western blot analysis of lysates from wild type (WT) and BUB1 knockout (KO) HeLa cells, using [KO Validated] BUB1 Rabbit polyclonal antibody (STJ11100026) at 1:1000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (STJS000856) at 1:10000 dilution. Lysates/proteins: 25 Mu g per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit. Exposure time: 1min.")
