| Host: |
Rabbit |
| Applications: |
WB |
| Reactivity: |
Human/Rat/Mouse |
| Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description: |
Rabbit polyclonal antibody anti-Germ cell nuclear acidic protein (444-494 aa) is suitable for use in Western Blot research applications. |
| Clonality: |
Polyclonal |
| Conjugation: |
Unconjugated |
| Isotype: |
IgG |
| Formulation: |
Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide. |
| Purification: |
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Concentration: |
1 mg/mL |
| Dilution Range: |
WB 1:500-2000 |
| Storage Instruction: |
Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: |
GCNA |
| Gene ID: |
93953 |
| Uniprot ID: |
GCNA_HUMAN |
| Immunogen Region: |
444-494 aa |
| Specificity: |
This antibody detects endogenous levels of ACRC at Human |
| Immunogen: |
Synthesized peptide derived from the human ACRC at the amino acid range 444-494 |
| Function | May play a role in DNA-protein cross-links (DPCs) clearance through a SUMO-dependent recruitment to sites of DPCs, ensuring the genomic stability by protecting germ cells and early embryos from various sources of damage. Can resolve the topoisomerase II (TOP2A) DPCs. |
| Protein Name | Germ Cell Nuclear Acidic ProteinAcidic Repeat-Containing ProteinGerm Cell Nuclear Acidic PeptidaseGerm Cell Nuclear Antigen |
| Cellular Localisation | NucleusPml BodyChromosomeCo-Localizes With Sumo2 At Pml Bodies In All Interphase CellsLocalizes On Condensed Chromosomes In Spermatocytes In G2 And M During Meiotic Prophase |
| Alternative Antibody Names | Anti-Germ Cell Nuclear Acidic Protein antibodyAnti-Acidic Repeat-Containing Protein antibodyAnti-Germ Cell Nuclear Acidic Peptidase antibodyAnti-Germ Cell Nuclear Antigen antibodyAnti-GCNA antibodyAnti-ACRC antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
