• Immunofluorescence analysis of PC-12 cells using FRAT1 Rabbit monoclonal antibody (STJ11104163) at dilution of 1:100 (40x lens). Secondary antibody: Cy3 Goat Anti-Rabbit IgG (H+L) at 1:500 dilution. Blue: DAPI for nuclear staining.
  • Immunofluorescence analysis of NIH/3T3 cells using FRAT1 Rabbit monoclonal antibody (STJ11104163) at dilution of 1:100 (40x lens). Secondary antibody: Cy3 Goat Anti-Rabbit IgG (H+L) at 1:500 dilution. Blue: DAPI for nuclear staining.
  • Immunofluorescence analysis of HeLa cells using FRAT1 Rabbit monoclonal antibody (STJ11104163) at dilution of 1:100 (40x lens). Secondary antibody: Cy3 Goat Anti-Rabbit IgG (H+L) at 1:500 dilution. Blue: DAPI for nuclear staining.

Anti-FRAT1 antibody (70-170) [S4163RM] (STJ11104163)

SKU:
STJ11104163

£146.50 - £639.50
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Host: Rabbit
Applications: IF
Reactivity: Human/Mouse/Rat
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description: Rabbit monoclonal antibody anti-Proto-Oncogene Frat1 (70-170) is suitable for use in Immunofluorescence research applications.
Clonality: Monoclonal
Clone ID: S4163RM
Conjugation: Unconjugated
Isotype: IgG
Formulation: PBS with 0.02% Sodium Azide, 0.05% BSA, 50% Glycerol, pH7.3.
Purification: Affinity purification
Dilution Range: IF/ICC 1:50-1:200
Storage Instruction: Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.
Gene Symbol: FRAT1
Gene ID: 10023
Uniprot ID: FRAT1_HUMAN
Immunogen Region: 70-170
Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 70-170 of human FRAT1 (NP_005470.2).
Immunogen Sequence: PLRAPGPLAAAVPADKARSP AVPLLLPPALAETVGPAPPG VLRCALGDRGRVRGRAAPYC VAELATGPSALSPLPPQADL DGPPGAGKQGIPQPLSGPCR R
Post Translational Modifications Phosphorylated.
Function Positively regulates the Wnt signaling pathway by stabilizing beta-catenin through the association with GSK-3. May play a role in tumor progression and collaborate with PIM1 and MYC in lymphomagenesis.
Protein Name Proto-Oncogene Frat1
Frequently Rearranged In Advanced T-Cell Lymphomas 1
Frat-1
Database Links Reactome: R-HSA-196299
Reactome: R-HSA-4641262
Cellular Localisation Cytoplasm
Alternative Antibody Names Anti-Proto-Oncogene Frat1 antibody
Anti-Frequently Rearranged In Advanced T-Cell Lymphomas 1 antibody
Anti-Frat-1 antibody
Anti-FRAT1 antibody

Information sourced from Uniprot.org

12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance