| Host: |
Rabbit |
| Applications: |
WB |
| Reactivity: |
Mouse/Rat |
| Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description: |
Rabbit polyclonal antibody anti-FRAT1 (C-Term) is suitable for use in Western Blot research applications. |
| Clonality: |
Polyclonal |
| Conjugation: |
Unconjugated |
| Isotype: |
IgG |
| Formulation: |
PBS with 0.01% Thimerosal, 50% Glycerol, pH7.3. |
| Purification: |
Affinity purification |
| Dilution Range: |
WB 1:500-1:2000 |
| Storage Instruction: |
Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: |
FRAT1 |
| Gene ID: |
10023 |
| Uniprot ID: |
FRAT1_HUMAN |
| Immunogen Region: |
C-Term |
| Immunogen: |
A synthetic peptide corresponding to a sequence within amino acids 200 to the C-terminus of human FRAT1 (NP_005470.2). |
| Immunogen Sequence: |
HRLLQQLVLSGNLIKEAVRR LHSRRLQLRAKLPQRPLLGP LSAPVHEPPSPRSPRAACSD PGASGRAQLRTGDGVLVPGS |
| Post Translational Modifications | Phosphorylated. |
| Function | Positively regulates the Wnt signaling pathway by stabilizing beta-catenin through the association with GSK-3. May play a role in tumor progression and collaborate with PIM1 and MYC in lymphomagenesis. |
| Protein Name | Proto-Oncogene Frat1Frequently Rearranged In Advanced T-Cell Lymphomas 1Frat-1 |
| Database Links | Reactome: R-HSA-196299Reactome: R-HSA-4641262 |
| Cellular Localisation | Cytoplasm |
| Alternative Antibody Names | Anti-Proto-Oncogene Frat1 antibodyAnti-Frequently Rearranged In Advanced T-Cell Lymphomas 1 antibodyAnti-Frat-1 antibodyAnti-FRAT1 antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
