| Host: |
Rabbit |
| Applications: |
WB |
| Reactivity: |
Human/Mouse |
| Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description: |
Rabbit polyclonal antibody anti-FBXO25 (142-291) is suitable for use in Western Blot research applications. |
| Clonality: |
Polyclonal |
| Conjugation: |
Unconjugated |
| Isotype: |
IgG |
| Formulation: |
PBS with 0.01% Thimerosal, 50% Glycerol, pH7.3. |
| Purification: |
Affinity purification |
| Dilution Range: |
WB 1:500-1:2000 |
| Storage Instruction: |
Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: |
FBXO25 |
| Gene ID: |
26260 |
| Uniprot ID: |
FBX25_HUMAN |
| Immunogen Region: |
142-291 |
| Immunogen: |
Recombinant fusion protein containing a sequence corresponding to amino acids 142-291 of human FBXO25 (NP_036305.2). |
| Immunogen Sequence: |
WQQQLQDLQMTKQVNNGLTL SDLPLHMLNNILYRFSDGWD IITLGQVTPTLYMLSEDRQL WKKLCQYHFAEKQFCRHLIL SEKGHIEWKLMYFALQKHYP AKEQYGDTLHFCRHCSILFW KDSGHPCTAADPDSCFTPVS PQHFIDLFKF |
| Tissue Specificity | Expressed in all brain tissue observed. |
| Function | Substrate-recognition component of the SCF (SKP1-CUL1-F-box protein)-type E3 ubiquitin ligase complex. May play a role in accumulation of expanded polyglutamine (polyQ) protein huntingtin (HTT). |
| Protein Name | F-Box Only Protein 25 |
| Cellular Localisation | NucleusIn The NucleusAssociates With A Subnuclear Dot-Like StructureColocalized With Skp1 |
| Alternative Antibody Names | Anti-F-Box Only Protein 25 antibodyAnti-FBXO25 antibodyAnti-FBX25 antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
