| Host: |
Rabbit |
| Applications: |
WB |
| Reactivity: |
Human |
| Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description: |
Rabbit polyclonal antibody anti-NGRN (62-291) is suitable for use in Western Blot research applications. |
| Clonality: |
Polyclonal |
| Conjugation: |
Unconjugated |
| Isotype: |
IgG |
| Formulation: |
PBS with 0.01% Thimerosal, 50% Glycerol, pH7.3. |
| Purification: |
Affinity purification |
| Dilution Range: |
WB 1:500-1:2000 |
| Storage Instruction: |
Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: |
NGRN |
| Gene ID: |
51335 |
| Uniprot ID: |
NGRN_HUMAN |
| Immunogen Region: |
62-291 |
| Immunogen: |
Recombinant fusion protein containing a sequence corresponding to amino acids 62-291 of human NGRN (NP_001028260.2). |
| Immunogen Sequence: |
QAIRFQKIRRQMEAPGAPPR TLTWEAMEQIRYLHEEFPES WSVPRLAEGFDVSTDVIRRV LKSKFLPTLEQKLKQDQKVL KKAGLAHSLQHLRGSGNTSK LLPAGHSVSGSLLMPGHEAS SKDPNHSTALKVIESDTHRT NTPRRRKGRNKEIQDLEESF VPVAAPLGHPRELQKYSSDS ESPRGTGSGALPSGQKLEEL KAEEPDNFSSKVVQRGREFF DSNGNFLYRI |
| Tissue Specificity | Expressed at high levels in heart, brain and skeletal muscle. In brain, mainly expressed in neurons rather than glial cells. |
| Function | Plays an essential role in mitochondrial ribosome biogenesis. As a component of a functional protein-RNA module, consisting of RCC1L, NGRN, RPUSD3, RPUSD4, TRUB2, FASTKD2 and 16S mitochondrial ribosomal RNA (16S mt-rRNA), controls 16S mt-rRNA abundance and is required for intra-mitochondrial translation of core subunits of the oxidative phosphorylation system. |
| Protein Name | NeugrinMesenchymal Stem Cell Protein Dsc92Neurite Outgrowth-Associated ProteinSpinal Cord-Derived Protein Fi58g |
| Cellular Localisation | NucleusSecretedMitochondrion Membrane |
| Alternative Antibody Names | Anti-Neugrin antibodyAnti-Mesenchymal Stem Cell Protein Dsc92 antibodyAnti-Neurite Outgrowth-Associated Protein antibodyAnti-Spinal Cord-Derived Protein Fi58g antibodyAnti-NGRN antibodyAnti-FI58G antibodyAnti-HT020 antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
