| Host: |
Rabbit |
| Applications: |
WB |
| Reactivity: |
Human/Mouse/Rat |
| Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description: |
Rabbit polyclonal antibody anti-FBXL14 (1-418) is suitable for use in Western Blot research applications. |
| Clonality: |
Polyclonal |
| Conjugation: |
Unconjugated |
| Isotype: |
IgG |
| Formulation: |
PBS with 0.01% Thimerosal, 50% Glycerol, pH7.3. |
| Purification: |
Affinity purification |
| Dilution Range: |
WB 1:500-1:2000 |
| Storage Instruction: |
Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: |
FBXL14 |
| Gene ID: |
144699 |
| Uniprot ID: |
FXL14_HUMAN |
| Immunogen Region: |
1-418 |
| Immunogen: |
Recombinant fusion protein containing a sequence corresponding to amino acids 1-418 of human FBXL14 (NP_689654.1). |
| Immunogen Sequence: |
METHISCLFPELLAMIFGYL DVRDKGRAAQVCTAWRDAAY HKSVWRGVEAKLHLRRANPS LFPSLQARGIRRVQILSLRR SLSYVIQGMANIESLNLSGC YNLTDNGLGHAFVQEIGSLR ALNLSLCKQITDSSLGRIAQ YLKGLEVLELGGCSNITNTG LLLIAWGLQRLKSLNLRSCR HLSDVGIGHLAGMTRSAAEG CLGLEQLTLQDCQKLTDLSL KHISRGLTGLRLLNLSFCG |
| Function | Substrate-recognition component of some SCF (SKP1-CUL1-F-box protein)-type E3 ubiquitin-protein ligase complexes. The SCF(FBXL14) complex acts by mediating ubiquitination and subsequent degradation of SNAI1. |
| Protein Name | F-Box/Lrr-Repeat Protein 14F-Box And Leucine-Rich Repeat Protein 14 |
| Database Links | Reactome: R-HSA-8951664Reactome: R-HSA-983168 |
| Cellular Localisation | Cytoplasm |
| Alternative Antibody Names | Anti-F-Box/Lrr-Repeat Protein 14 antibodyAnti-F-Box And Leucine-Rich Repeat Protein 14 antibodyAnti-FBXL14 antibodyAnti-FBL14 antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
