• Western blot analysis of extracts of HeLa cells, using EXOC1 Antibody (STJ116329) at 1:3000 dilution. Secondary antibody: HRP Goat Anti-rabbit IgG (H+L) at 1:10000 dilution. Lysates/proteins: 25ug per lane. Blocking buffer: 3% non-fat dry milk in TBST. Detection: ECL Enhanced Kit. Exposure time: 90s.
  • Western blot analysis of lysates from mouse brain, using EXOC1 Rabbit polyclonal antibody (STJ116329) at 1:3000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (STJS000856) at 1:10000 dilution. Lysates/proteins: 25 Mu g per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit. Exposure time: 90s.
  • Western blot analysis of extracts of mouse brain, using EXOC1 Antibody (STJ116329) at 1:3000 dilution. Secondary antibody: HRP Goat Anti-rabbit IgG (H+L) at 1:10000 dilution. Lysates/proteins: 25ug per lane. Blocking buffer: 3% non-fat dry milk in TBST. Detection: ECL Basic Kit. Exposure time: 90s.
  • Western blot analysis of lysates from HeLa cells, using EXOC1 Rabbit polyclonal antibody (STJ116329) at 1:3000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (STJS000856) at 1:10000 dilution. Lysates/proteins: 25 Mu g per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Enhanced Kit. Exposure time: 90s.

Anti-EXOC1 antibody (645-894) (STJ116329)

SKU:
STJ116329

£169.50 - £449.50
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Host: Rabbit
Applications: WB
Reactivity: Human/Mouse
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description: Rabbit polyclonal antibody anti-EXOC1 (645-894) is suitable for use in Western Blot research applications.
Clonality: Polyclonal
Conjugation: Unconjugated
Isotype: IgG
Formulation: PBS with 0.01% Thimerosal, 50% Glycerol, pH7.3.
Purification: Affinity purification
Dilution Range: WB 1:500-1:2000
Storage Instruction: Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.
Gene Symbol: EXOC1
Gene ID: 55763
Uniprot ID: EXOC1_HUMAN
Immunogen Region: 645-894
Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 645-894 of human EXOC1 (NP_001020095.1).
Immunogen Sequence: RNFDKCISNQIRQMEEVKIS KKSKVGILPFVAEFEEFAGL AESIFKNAERRGDLDKAYTK LIRGVFVNVEKVANESQKTP RDVVMMENFHHIFATLSRLK ISCLEAEKKEAKQKYTDHLQ SYVIYSLGQPLEKLNHFFEG VEARVAQGIREEEVSYQLAF NKQELRKVIKEYPGKEVKKG LDNLYKKVDKHLCEEENLLQ VVWHSMQDEFIRQYKHFEGL IARCYPGSGVTMEFTIQDI
Function Component of the exocyst complex involved in the docking of exocytic vesicles with fusion sites on the plasma membrane. (Microbial infection) Has an antiviral effect against flaviviruses by affecting viral RNA transcription and translation through the sequestration of elongation factor 1-alpha (EEF1A1). This results in decreased viral RNA synthesis and decreased viral protein translation.
Protein Name Exocyst Complex Component 1
Exocyst Complex Component Sec3
Database Links Reactome: R-HSA-1445148
Reactome: R-HSA-264876
Reactome: R-HSA-5620916
Cellular Localisation Midbody
Midbody Ring
Cytoplasm
Perinuclear Region
Cell Membrane
Colocalizes With Cntrl/Centriolin At The Midbody Ring
Localizes In Cell Membrane In The Presence Of Slc6a9
Alternative Antibody Names Anti-Exocyst Complex Component 1 antibody
Anti-Exocyst Complex Component Sec3 antibody
Anti-EXOC1 antibody
Anti-SEC3 antibody
Anti-SEC3L1 antibody
Anti-BM-012 antibody

Information sourced from Uniprot.org

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