Host: |
Rabbit |
Applications: |
WB |
Reactivity: |
Human |
Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Short Description: |
Rabbit polyclonal antibody anti-ERAP2 (1-170) is suitable for use in Western Blot research applications. |
Clonality: |
Polyclonal |
Conjugation: |
Unconjugated |
Isotype: |
IgG |
Formulation: |
PBS with 0.01% Thimerosal, 50% Glycerol, pH7.3. |
Purification: |
Affinity purification |
Dilution Range: |
WB 1:500-1:2000 |
Storage Instruction: |
Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Gene Symbol: |
ERAP2 |
Gene ID: |
64167 |
Uniprot ID: |
ERAP2_HUMAN |
Immunogen Region: |
1-170 |
Immunogen: |
Recombinant fusion protein containing a sequence corresponding to amino acids 1-170 of human ERAP2 (NP_071745.1). |
Immunogen Sequence: |
MFHSSAMVNSHRKPMFNIHR GFYCLTAILPQICICSQFSV PSSYHFTEDPGAFPVATNGE RFPWQELRLPSVVIPLHYDL FVHPNLTSLDFVASEKIEVL VSNATQFIILHSKDLEITNA TLQSEEDSRYMKPGKELKVL SYPAHEQIALLVPEKLTPHL KYYVAMDFQA |
Post Translational Modifications | N-glycosylated. |
Function | Aminopeptidase that plays a central role in peptide trimming, a step required for the generation of most HLA class I-binding peptides. Peptide trimming is essential to customize longer precursor peptides to fit them to the correct length required for presentation on MHC class I molecules. Preferentially hydrolyzes the basic residues Arg and Lys. |
Protein Name | Endoplasmic Reticulum Aminopeptidase 2Leukocyte-Derived Arginine AminopeptidaseL-Rap |
Database Links | Reactome: R-HSA-983170 |
Cellular Localisation | Endoplasmic Reticulum MembraneSingle-Pass Type Ii Membrane Protein |
Alternative Antibody Names | Anti-Endoplasmic Reticulum Aminopeptidase 2 antibodyAnti-Leukocyte-Derived Arginine Aminopeptidase antibodyAnti-L-Rap antibodyAnti-ERAP2 antibodyAnti-LRAP antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance