| Host: |
Rabbit |
| Applications: |
WB |
| Reactivity: |
Human/Mouse/Rat |
| Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description: |
Rabbit polyclonal antibody anti-ENTPD4 (350-470) is suitable for use in Western Blot research applications. |
| Clonality: |
Polyclonal |
| Conjugation: |
Unconjugated |
| Isotype: |
IgG |
| Formulation: |
PBS with 0.01% Thimerosal, 50% Glycerol, pH7.3. |
| Purification: |
Affinity purification |
| Dilution Range: |
WB 1:500-1:2000 |
| Storage Instruction: |
Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: |
ENTPD4 |
| Gene ID: |
9583 |
| Uniprot ID: |
ENTP4_HUMAN |
| Immunogen Region: |
350-470 |
| Immunogen: |
Recombinant fusion protein containing a sequence corresponding to amino acids 350-470 of human ENTPD4 (NP_001122402.1). |
| Immunogen Sequence: |
LTPDMPYLDPCLPLDIKDEI QQNGQTIYLRGTGDFDLCRE TIQPFMNKTNETQTSLNGVY QPPIHFQNSEFYGFSEFYYC TEDVLRMGGDYNAAKFTKAA KDYCATKWSILRERFDRGLY A |
| Tissue Specificity | Ubiquitous. Highest expression in testis and lowest in bladder. |
| Function | Isoform 1: Catalyzes the hydrolysis of nucleoside triphosphates and diphosphates in a calcium- or magnesium-dependent manner, with a preference for pyrimidines. Preferentially hydrolyzes UTP and TTP. AMP, ADP, ATP and UMP are not substrates. Preferentially activated by Ca(2+) over Mg(2+). Isoform 2: Has a broad substrate specificity with the ability of cleaving all nucleotide di- and triphosphates with the exception of adenosine di- and triphosphate (ADP and ATP). Preferentially hydrolyzes CTP, UDP, CDP, GTP and GDP. Can use either Ca(2+) or Mg(2+) equally. |
| Protein Name | Ectonucleoside Triphosphate Diphosphohydrolase 4Ntpdase 4Golgi UdpaseLysosomal Apyrase-Like Protein Of 70 KdaUridine-DiphosphataseUdpase |
| Database Links | Reactome: R-HSA-8850843 |
| Cellular Localisation | Isoform 1: Cytoplasmic VesicleAutophagosome MembraneMulti-Pass Membrane ProteinLysosome MembraneIsoform 2: Golgi Apparatus Membrane |
| Alternative Antibody Names | Anti-Ectonucleoside Triphosphate Diphosphohydrolase 4 antibodyAnti-Ntpdase 4 antibodyAnti-Golgi Udpase antibodyAnti-Lysosomal Apyrase-Like Protein Of 70 Kda antibodyAnti-Uridine-Diphosphatase antibodyAnti-Udpase antibodyAnti-ENTPD4 antibodyAnti-KIAA0392 antibodyAnti-LALP70 antibodyAnti-LYSAL1 antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
