| Host: |
Rabbit |
| Applications: |
WB |
| Reactivity: |
Human |
| Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description: |
Rabbit polyclonal antibody anti-EMILIN1 (817-1016) is suitable for use in Western Blot research applications. |
| Clonality: |
Polyclonal |
| Conjugation: |
Unconjugated |
| Isotype: |
IgG |
| Formulation: |
PBS with 0.02% Sodium Azide, 50% Glycerol, pH7.3. |
| Purification: |
Affinity purification |
| Dilution Range: |
WB 1:200-1:2000 |
| Storage Instruction: |
Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: |
EMILIN1 |
| Gene ID: |
11117 |
| Uniprot ID: |
EMIL1_HUMAN |
| Immunogen Region: |
817-1016 |
| Immunogen: |
Recombinant fusion protein containing a sequence corresponding to amino acids 817-1016 of human EMILIN1 (NP_008977.1). |
| Immunogen Sequence: |
GEAGPPGPPGLQGPPGPAGP PGSPGKDGQEGPIGPPGPQG EQGVEGAPAAPVPQVAFSAA LSLPRSEPGTVPFDRVLLND GGYYDPETGVFTAPLAGRYL LSAVLTGHRHEKVEAVLSRS NQGVARVDSGGYEPEGLENK PVAESQPSPGTLGVFSLILP LQAGDTVCVDLVMGQLAHSE EPLTIFSGALLYGDPELEHA |
| Tissue Specificity | Distributed in tissues where resilience and elastic recoil are prominent. Highest levels in the adult small intestine, aorta, lung, uterus, and appendix and in the fetal spleen, kidney, lung, and heart.intermediate expression was detected in adult liver, ovary, colon, stomach, lymph node and spleen.adult heart, bladder, prostate, adrenal gland, mammary gland, placenta and kidney showed low expression whereas a series of other adult tissues, including skeletal muscle and different regions of adult brain show no expression. Detected in intramuscular nerve bundles, where it particularly localizes in the epineurium, the most external layer of dense connective tissue enclosing the nerve. |
| Function | May be responsible for anchoring smooth muscle cells to elastic fibers, and may be involved not only in the formation of the elastic fiber, but also in the processes that regulate vessel assembly. Has cell adhesive capacity. |
| Protein Name | Emilin-1Elastin Microfibril Interface-Located Protein 1Elastin Microfibril Interfacer 1 |
| Database Links | Reactome: R-HSA-2129379 |
| Cellular Localisation | SecretedExtracellular SpaceExtracellular MatrixFound Mainly At The Interface Between Amorphous Elastin And Microfibrils |
| Alternative Antibody Names | Anti-Emilin-1 antibodyAnti-Elastin Microfibril Interface-Located Protein 1 antibodyAnti-Elastin Microfibril Interfacer 1 antibodyAnti-EMILIN1 antibodyAnti-EMI antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
